3V6A
 
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1J2Z
 | | Crystal structure of UDP-N-acetylglucosamine acyltransferase | | Descriptor: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, L(+)-TARTARIC ACID, SULFATE ION, ... | | Authors: | Lee, B.I, Suh, S.W. | | Deposit date: | 2003-01-15 | | Release date: | 2004-01-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori
Proteins, 53, 2003
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2HGH
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6KEI
 | | Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 16-methoxy-11-methyl-6-[(pyridin-2-yl)methoxy]-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(16),3,5,7,9,13(17),14-heptaen-12-one | | Descriptor: | 16-methoxy-11-methyl-6-[(pyridin-2-yl)methoxy]-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(16),3,5,7,9,13(17),14-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID | | Authors: | Lee, B.I, Park, T.H. | | Deposit date: | 2019-07-04 | | Release date: | 2020-07-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.451 Å) | | Cite: | Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research.
Molecules, 26, 2021
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7OGT
 | | Folded elbow of cohesin | | Descriptor: | Structural maintenance of chromosomes protein 1, Structural maintenance of chromosomes protein 3 | | Authors: | Lee, B.-G, Gonzalez Llamazares, A, Collier, J, Patele, N.J, Nasmyth, K.A, Lowe, J. | | Deposit date: | 2021-05-07 | | Release date: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes.
Elife, 10, 2021
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6L4O
 | | Crystal structure of API5-FGF2 complex | | Descriptor: | Apoptosis inhibitor 5, Fibroblast growth factor 2 | | Authors: | Lee, B.I, Bong, S.M. | | Deposit date: | 2019-10-18 | | Release date: | 2020-04-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Regulation of mRNA export through API5 and nuclear FGF2 interaction.
Nucleic Acids Res., 48, 2020
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6YVV
 | | Condensin complex from S.cerevisiae ATP-free apo bridged state | | Descriptor: | Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2, ... | | Authors: | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Haering, C.H, Aragon, L, Lowe, J. | | Deposit date: | 2020-04-28 | | Release date: | 2020-07-15 | | Last modified: | 2020-08-19 | | Method: | ELECTRON MICROSCOPY (7.5 Å) | | Cite: | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
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6YVU
 | | Condensin complex from S.cerevisiae ATP-free apo non-engaged state | | Descriptor: | Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2,Smc2, ... | | Authors: | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Aragon, L, Haering, C.H, Lowe, J. | | Deposit date: | 2020-04-28 | | Release date: | 2020-07-15 | | Last modified: | 2020-08-19 | | Method: | ELECTRON MICROSCOPY (7.5 Å) | | Cite: | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
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4QXZ
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4RSS
 | | Crystal structure of tyrosine-protein kinase SYK with an inhibitor | | Descriptor: | 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-1H-pyrazol-4-yl)methyl]azetidin-3-ol, Tyrosine-protein kinase SYK | | Authors: | Lee, B.I, Lee, S.J, Choi, J.-S. | | Deposit date: | 2014-11-11 | | Release date: | 2015-10-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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4XGQ
 | | Crystal structure of addiction module from Mycobacterial species | | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | | Deposit date: | 2015-01-02 | | Release date: | 2015-08-12 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
Nucleic Acids Res., 43, 2015
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4XGR
 | | Crystal structure of addiction module from Mycobacterial species | | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | | Deposit date: | 2015-01-02 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
Nucleic Acids Res., 43, 2015
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7BWF
 | | YoeB-YefM complex from Staphylococcus aureus | | Descriptor: | Addiction module antitoxin RelB, Antitoxin | | Authors: | Lee, B.-J, Eun, H.-J. | | Deposit date: | 2020-04-14 | | Release date: | 2020-05-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the YoeBSa1-YefMSa1 complex from Staphylococcus aureus.
Biochem.Biophys.Res.Commun., 527, 2020
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7CC7
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4Z1D
 | | Structure of PEP and zinc bound KDO8PS from H.pylori | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHOENOLPYRUVATE, ZINC ION | | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | | Deposit date: | 2015-03-27 | | Release date: | 2016-03-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS).
Eur.J.Med.Chem., 108, 2016
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4Z1C
 | | Structure of Cadmium bound KDO8PS from H.pylori | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION | | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | | Deposit date: | 2015-03-27 | | Release date: | 2016-03-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS).
Eur.J.Med.Chem., 108, 2016
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4Z1B
 | | Structure of H204A mutant KDO8PS from H.pylori | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase | | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | | Deposit date: | 2015-03-27 | | Release date: | 2016-03-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS).
Eur.J.Med.Chem., 108, 2016
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4Z1A
 | | Structure of apo form KDO8PS from H.pylori | | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase | | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | | Deposit date: | 2015-03-27 | | Release date: | 2016-03-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS).
Eur.J.Med.Chem., 108, 2016
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6ZZ6
 | | Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (34-MER), MAGNESIUM ION, ... | | Authors: | Lee, B.-G, Gonzalez Llamazares, A, Collier, J, Nasmyth, K.A, Lowe, J. | | Deposit date: | 2020-08-04 | | Release date: | 2020-09-30 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3.
Elife, 9, 2020
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7P81
 | | Crystal structure of ClpP from Bacillus subtilis in complex with ADEP2 (compact state) | | Descriptor: | ADEP2, ATP-dependent Clp protease proteolytic subunit | | Authors: | Lee, B.-G, Kim, L, Kim, M.K, Kwon, D.H, Song, H.K. | | Deposit date: | 2021-07-21 | | Release date: | 2022-06-29 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
Embo J., 41, 2022
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7P80
 | | Crystal structure of ClpP from Bacillus subtilis in complex with ADEP2 (compressed state) | | Descriptor: | ADEP2, ATP-dependent Clp protease proteolytic subunit | | Authors: | Lee, B.-G, Kim, L, Kim, M.K, Kwon, D.H, Song, H.K. | | Deposit date: | 2021-07-21 | | Release date: | 2022-06-29 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis.
Embo J., 41, 2022
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7Q2X
 | | Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (Form I) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ... | | Authors: | Lee, B.-G, Rhodes, J, Lowe, J. | | Deposit date: | 2021-10-26 | | Release date: | 2022-03-23 | | Last modified: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Clamping of DNA shuts the condensin neck gate.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Q2Y
 | | Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (form II) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ... | | Authors: | Lee, B.-G, Rhodes, J, Lowe, J. | | Deposit date: | 2021-10-26 | | Release date: | 2022-03-23 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Clamping of DNA shuts the condensin neck gate.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Q2Z
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3CNK
 | | Crystal Structure of the dimerization domain of human filamin A | | Descriptor: | Filamin-A, SULFATE ION | | Authors: | Lee, B.J, Seo, M.D, Seok, S.H, Lee, S.J, Kwon, A.R, Im, H. | | Deposit date: | 2008-03-26 | | Release date: | 2009-02-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of the dimerization domain of human filamin A
Proteins, 75, 2008
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