4XGQ
| Crystal structure of addiction module from Mycobacterial species | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | Deposit date: | 2015-01-02 | Release date: | 2015-08-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides Nucleic Acids Res., 43, 2015
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4XGR
| Crystal structure of addiction module from Mycobacterial species | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | Deposit date: | 2015-01-02 | Release date: | 2015-08-12 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides Nucleic Acids Res., 43, 2015
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3KTJ
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4LTT
| Crystal structure of native apo toxin from Helicobacter pylori | Descriptor: | Uncharacterized protein, toxin | Authors: | Lee, B.J, Im, H, Pathak, C.C, Yoon, H.J. | Deposit date: | 2013-07-23 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Crystal structure of apo and copper bound HP0894 toxin from Helicobacter pylori 26695 and insight into mRNase activity Biochim.Biophys.Acta, 1834, 2013
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7OGT
| Folded elbow of cohesin | Descriptor: | Structural maintenance of chromosomes protein 1, Structural maintenance of chromosomes protein 3 | Authors: | Lee, B.-G, Gonzalez Llamazares, A, Collier, J, Patele, N.J, Nasmyth, K.A, Lowe, J. | Deposit date: | 2021-05-07 | Release date: | 2021-07-28 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes. Elife, 10, 2021
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7P81
| Crystal structure of ClpP from Bacillus subtilis in complex with ADEP2 (compact state) | Descriptor: | ADEP2, ATP-dependent Clp protease proteolytic subunit | Authors: | Lee, B.-G, Kim, L, Kim, M.K, Kwon, D.H, Song, H.K. | Deposit date: | 2021-07-21 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
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7P80
| Crystal structure of ClpP from Bacillus subtilis in complex with ADEP2 (compressed state) | Descriptor: | ADEP2, ATP-dependent Clp protease proteolytic subunit | Authors: | Lee, B.-G, Kim, L, Kim, M.K, Kwon, D.H, Song, H.K. | Deposit date: | 2021-07-21 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
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6ZZ6
| Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (34-MER), MAGNESIUM ION, ... | Authors: | Lee, B.-G, Gonzalez Llamazares, A, Collier, J, Nasmyth, K.A, Lowe, J. | Deposit date: | 2020-08-04 | Release date: | 2020-09-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3. Elife, 9, 2020
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6YVU
| Condensin complex from S.cerevisiae ATP-free apo non-engaged state | Descriptor: | Condensin complex subunit 1,Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2,Smc2, ... | Authors: | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Aragon, L, Haering, C.H, Lowe, J. | Deposit date: | 2020-04-28 | Release date: | 2020-07-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nat.Struct.Mol.Biol., 27, 2020
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6YVV
| Condensin complex from S.cerevisiae ATP-free apo bridged state | Descriptor: | Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2, ... | Authors: | Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Haering, C.H, Aragon, L, Lowe, J. | Deposit date: | 2020-04-28 | Release date: | 2020-07-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nat.Struct.Mol.Biol., 27, 2020
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4QXZ
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3KTI
| Structure of ClpP in complex with ADEP1 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 1, ... | Authors: | Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. | Deposit date: | 2009-11-25 | Release date: | 2010-03-23 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
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3KTK
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3KTG
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3KTH
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4RSS
| Crystal structure of tyrosine-protein kinase SYK with an inhibitor | Descriptor: | 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-1H-pyrazol-4-yl)methyl]azetidin-3-ol, Tyrosine-protein kinase SYK | Authors: | Lee, B.I, Lee, S.J, Choi, J.-S. | Deposit date: | 2014-11-11 | Release date: | 2015-10-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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4Z1D
| Structure of PEP and zinc bound KDO8PS from H.pylori | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHOENOLPYRUVATE, ZINC ION | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | Deposit date: | 2015-03-27 | Release date: | 2016-03-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016
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7Q2X
| Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (Form I) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ... | Authors: | Lee, B.-G, Rhodes, J, Lowe, J. | Deposit date: | 2021-10-26 | Release date: | 2022-03-23 | Last modified: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Clamping of DNA shuts the condensin neck gate. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Q2Y
| Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (form II) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Condensin complex subunit 1, ... | Authors: | Lee, B.-G, Rhodes, J, Lowe, J. | Deposit date: | 2021-10-26 | Release date: | 2022-03-23 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Clamping of DNA shuts the condensin neck gate. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Q2Z
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4Z1B
| Structure of H204A mutant KDO8PS from H.pylori | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | Deposit date: | 2015-03-27 | Release date: | 2016-03-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016
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4Z1C
| Structure of Cadmium bound KDO8PS from H.pylori | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | Deposit date: | 2015-03-27 | Release date: | 2016-03-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016
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4Z1A
| Structure of apo form KDO8PS from H.pylori | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase | Authors: | Lee, B.J, Cho, S, Im, H, Yoon, H.J. | Deposit date: | 2015-03-27 | Release date: | 2016-03-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS). Eur.J.Med.Chem., 108, 2016
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3CNK
| Crystal Structure of the dimerization domain of human filamin A | Descriptor: | Filamin-A, SULFATE ION | Authors: | Lee, B.J, Seo, M.D, Seok, S.H, Lee, S.J, Kwon, A.R, Im, H. | Deposit date: | 2008-03-26 | Release date: | 2009-02-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of the dimerization domain of human filamin A Proteins, 75, 2008
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3V6A
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