4Z1D

Structure of PEP and zinc bound KDO8PS from H.pylori

Summary for 4Z1D

• Entry DOI: 10.2210/pdb4z1d/pdb
• Related: 4Z1A 4Z1B 4Z1C
• Descriptor: 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHOENOLPYRUVATE, ZINC ION, ... (4 entities in total)
• Functional Keywords: helicobacter pylori, lipopolysaccharide biosynthesis, ligand bound, transferase
• Biological source: Helicobacter pylori (strain ATCC 700392 / 26695)
• Total number of polymer chains: 2
• Total formula weight: 61230.73

Authors

Lee, B.J.,Cho, S.,Im, H.,Yoon, H.J. (deposition date: 2015-03-27, release date: 2016-03-09, Last modification date: 2024-03-20)

• Primary citation: Cho, S.,Im, H.,Lee, K.Y.,Chen, J.,Kang, H.J.,Yoon, H.J.,Min, K.H.,Lee, K.R.,Park, H.J.,Lee, B.J.; Identification of novel scaffolds for potential anti-Helicobacter pylori agents based on the crystal structure of H. pylori 3-deoxy-d-manno-octulosonate 8-phosphate synthase (HpKDO8PS).; Eur.J.Med.Chem., 108:188-202, 2016; PubMed: 26649906; DOI: 10.1016/j.ejmech.2015.11.036

Experimental method

X-RAY DIFFRACTION (1.65 Å)