5F1B

Structural basis of Ebola virus entry: viral glycoprotein bound to its endosomal receptor Niemann-Pick C1

Summary for 5F1B

• Entry DOI: 10.2210/pdb5f1b/pdb
• Related: 5F18
• Descriptor: GP1, GP2, Niemann-Pick C1 protein, ... (5 entities in total)
• Functional Keywords: ebola virus, glycoprotein, npc1-c, viral protein-transport protein complex, viral protein/transport protein
• Biological source: Zaire ebolavirus (ZEBOV); More
• Cellular location: GP2: Virion membrane ; Single- pass type I membrane protein . GP1: Virion membrane ; Peripheral membrane protein . GP2-delta: Secreted : P87666 P87666; Late endosome membrane ; Multi-pass membrane protein : O15118
• Total number of polymer chains: 3
• Total formula weight: 61938.33

Authors

Wang, H.,Shi, Y.,Song, J.,Qi, J.,Lu, G.,Yan, J.,Gao, G.F. (deposition date: 2015-11-30, release date: 2016-01-20, Last modification date: 2023-11-08)

• Primary citation: Wang, H.,Shi, Y.,Song, J.,Qi, J.,Lu, G.,Yan, J.,Gao, G.F.; Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.; Cell, 164:258-268, 2016; PubMed: 26771495; DOI: 10.1016/j.cell.2015.12.044

Experimental method

X-RAY DIFFRACTION (2.3 Å)