5C6D
Crystal structure of USP7 in complex with UHRF1
Summary for 5C6D
Entry DOI | 10.2210/pdb5c6d/pdb |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 7, E3 ubiquitin-protein ligase UHRF1 (3 entities in total) |
Functional Keywords | usp7, uhrf1, hydrolase-ligase complex, hydrolase/ligase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q93009 Q96T88 |
Total number of polymer chains | 4 |
Total formula weight | 81486.19 |
Authors | Zhang, Z.-M.,Song, J. (deposition date: 2015-06-22, release date: 2015-09-09, Last modification date: 2023-09-27) |
Primary citation | Zhang, Z.M.,Rothbart, S.B.,Allison, D.F.,Cai, Q.,Harrison, J.S.,Li, L.,Wang, Y.,Strahl, B.D.,Wang, G.G.,Song, J. An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Rep, 12:1400-1406, 2015 Cited by PubMed: 26299963DOI: 10.1016/j.celrep.2015.07.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.292 Å) |
Structure validation
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