5C6D

Crystal structure of USP7 in complex with UHRF1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ubiquitin carboxyl-terminal hydrolase 7	polymer	322	37361.3	2	UniProt (Q93009) Pfam (PF12436) In PDB	Homo sapiens (Human)	Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
2	C, D	E3 ubiquitin-protein ligase UHRF1	polymer	33	3381.8	2	UniProt (Q96T88) In PDB	Homo sapiens (Human)	Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,hNp95,RING finger protein 106,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1
3		water	water		18.0	118	Chemie (HOH)

Sequence modifications

A, B: 561 - 881 (UniProt: Q93009)

PDB	External Database	Details
Ser 560	-	expression tag

C, D: 647 - 678 (UniProt: Q96T88)

PDB	External Database	Details
Ser 646	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	81486.2
All*	Total formula weight	81486.2

*Water molecules are not included.