5GZN

Structure of neutralizing antibody bound to Zika envelope protein

Summary for 5GZN

• Entry DOI: 10.2210/pdb5gzn/pdb
• Related: 5GZO
• Descriptor: Genome polyprotein, Antibody Heavy chain, Antibody light chain (3 entities in total)
• Functional Keywords: zika virus, human neutralizing antibody, envelope protein, molecular determinants, viral protein-immune system complex, viral protein/immune system
• Biological source: Zika virus (ZIKV); More
• Total number of polymer chains: 8
• Total formula weight: 272911.24

Authors

Wang, Q.,Yang, H.,Liu, X.,Dai, L.,Ma, T.,Qi, J.,Wong, G.,Peng, R.,Liu, S.,Li, J.,Li, S.,Song, J.,Liu, J.,He, J.,Yuan, H.,Xiong, Y.,Liao, Y.,Li, J.,Yang, J.,Tong, Z.,Griffin, B.,Bi, Y.,Liang, M.,Xu, X.,Cheng, G.,Wang, P.,Qiu, X.,Kobinger, G.,Shi, Y.,Yan, J.,Gao, G.F. (deposition date: 2016-09-29, release date: 2016-12-28, Last modification date: 2023-11-08)

• Primary citation: Wang, Q.,Yang, H.,Liu, X.,Dai, L.,Ma, T.,Qi, J.,Wong, G.,Peng, R.,Liu, S.,Li, J.,Li, S.,Song, J.,Liu, J.,He, J.,Yuan, H.,Xiong, Y.,Liao, Y.,Li, J.,Yang, J.,Tong, Z.,Griffin, B.D.,Bi, Y.,Liang, M.,Xu, X.,Qin, C.,Cheng, G.,Zhang, X.,Wang, P.,Qiu, X.,Kobinger, G.,Shi, Y.,Yan, J.,Gao, G.F.; Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus; Sci Transl Med, 8:369ra179-369ra179, 2016; PubMed: 27974667; DOI: 10.1126/scitranslmed.aai8336

Experimental method

X-RAY DIFFRACTION (3 Å)