7K7H

Density-fitted Model Structure of Antibody Variable Domains of TyTx1 in Complex with PltB pentamer of Typhoid Toxin

Summary for 7K7H

• Entry DOI: 10.2210/pdb7k7h/pdb
• EMDB information: 22699
• Descriptor: Pertussis like toxin subunit B, Fab Light Chain Variable Domain, Fab Heavy Chain Variable Domain, ... (4 entities in total)
• Functional Keywords: typhoid toxin, a2b5, antibody, fab, toxin
• Biological source: Salmonella enterica subsp. enterica serovar Typhi str. CT18; More
• Total number of polymer chains: 8
• Total formula weight: 89962.71

Authors

Nguyen, T.,Feathers, J.R.,Fromme, J.C.,Song, J. (deposition date: 2020-09-22, release date: 2021-09-01, Last modification date: 2021-09-22)

• Primary citation: Nguyen, T.,Richards, A.F.,Neupane, D.P.,Feathers, J.R.,Yang, Y.A.,Sim, J.H.,Byun, H.,Lee, S.,Ahn, C.,Van Slyke, G.,Fromme, J.C.,Mantis, N.J.,Song, J.; The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits.; Cell Rep, 36:109654-109654, 2021; PubMed: 34496256; DOI: 10.1016/j.celrep.2021.109654

Experimental method

ELECTRON MICROSCOPY (3 Å)