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PDB: 773 件
7TBZ
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The structure of ABCA1 Y482C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
7TBY
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The structure of human ABCA1 in nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ...
著者Sun, Y, Li, X.
登録日2021-12-22
公開日2022-01-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
6L4S
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BU of 6l4s by Molmil
cryo-em structure of alpha-synuclein fiber mutation type E46K
分子名称: Alpha-synuclein
著者Li, Y.W, Zhao, K, Liu, C, Li, X.
登録日2019-10-21
公開日2020-04-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Parkinson's disease associated mutation E46K of alpha-synuclein triggers the formation of a distinct fibril structure.
Nat Commun, 11, 2020
6LH8
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BU of 6lh8 by Molmil
Structure of aerolysin-like protein (Bombina maxima)
分子名称: aerolysin-like protein
著者Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
登録日2019-12-07
公開日2020-06-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.729 Å)
主引用文献A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
6LHZ
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BU of 6lhz by Molmil
Structure of aerolysin-like protein (Bombina maxima)
分子名称: aerolysin-like protein
著者Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
登録日2019-12-10
公開日2020-06-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
6E7P
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BU of 6e7p by Molmil
cryo-EM structure of human TRPML1 with PI35P2
分子名称: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], Mucolipin-1
著者Schmiege, P, Li, X.
登録日2018-07-27
公開日2018-11-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Y
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BU of 6e7y by Molmil
cryo-EM structure of human TRPML1 with PI45P2
分子名称: Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Schmiege, P, Li, X.
登録日2018-07-27
公開日2018-11-28
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
6E7Z
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cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2
分子名称: (1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl bis[dihydrogen (phosphate)], 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1
著者Schmiege, P, Li, X.
登録日2018-07-27
公開日2018-11-28
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Structural basis for PtdInsP2-mediated human TRPML1 regulation.
Nat Commun, 9, 2018
8WFN
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BU of 8wfn by Molmil
Cryo-EM structure of DSR2-TTP
分子名称: SIR2-like domain-containing protein, tail tube protein(TTP)
著者Zhang, H, Li, Z, Li, X.Z.
登録日2023-09-19
公開日2024-05-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.48 Å)
主引用文献Cryo-EM structure of DSR2-TTP
To Be Published
8XJM
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BU of 8xjm by Molmil
Latanoprost acid bound Prostaglandin F2-alpha receptor-Gq Protein Complex
分子名称: Antibody fragment scFv16, Engineered miniGq, Fusion tag,Prostaglandin F2-alpha receptor,LgBiT, ...
著者Zhang, X, Li, X, Liu, G, Gong, W.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJK
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Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex
分子名称: (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
著者Zhang, X, Li, X, Liu, G, Gong, W.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJN
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Cloprosetnol bound Thromboxane A2 receptor-Gq Protein Complex
分子名称: (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
著者Zhang, X, Li, X, Liu, G, Gong, W.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJO
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U46619 bound Thromboxane A2 receptor-Gq Protein Complex
分子名称: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
著者Zhang, X, Li, X, Liu, G, Gong, W.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
8XJL
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BU of 8xjl by Molmil
PGF2-alpha bound Prostaglandin F2-alpha receptor-Gq Protein Complex
分子名称: (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
著者Zhang, X, Li, X, Liu, G, Gong, W.
登録日2023-12-21
公開日2024-02-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
6KY4
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BU of 6ky4 by Molmil
Crystal structure of Sulfiredoxin from Arabidopsis thaliana
分子名称: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Sulfiredoxin, ...
著者Liu, M, Wang, J, Li, X, Li, M, Sylvanno, M.J, Zhang, M, Wang, M.
登録日2019-09-16
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of sulfiredoxin from Arabidopsis thaliana revealed a more robust antioxidant mechanism in plants.
Biochem.Biophys.Res.Commun., 520, 2019
8W4U
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BU of 8w4u by Molmil
human KCNQ2-CaM in complex with PIP2 and HN37
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
著者Ma, D, Li, X, Guo, J.
登録日2023-08-25
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8HS8
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BU of 8hs8 by Molmil
a bacteria protein complex
分子名称: CRISPR-associated endonuclease Cas9, a protein
著者Zhang, H, Li, X.Z, Song, G.Y.
登録日2022-12-17
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献a bacteria protein
To Be Published
6LML
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BU of 6lml by Molmil
Cryo-EM structure of the human glucagon receptor in complex with Gi1
分子名称: Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B.
登録日2019-12-26
公開日2020-04-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of Gsand Girecognition by the human glucagon receptor.
Science, 367, 2020
9AYB
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BU of 9ayb by Molmil
Structure of Apo Sialin S61A mutant
分子名称: Sialin
著者Schmiege, P, Li, X.
登録日2024-03-07
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structure of Apo Sialin S61A mutant
To Be Published
5JYY
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BU of 5jyy by Molmil
Structure-based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-resistant Influenza Viruses
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-[(2-methoxyethyl)carbamoyl]-D-glycero-D-galacto-non-2-enon ic acid, CALCIUM ION, ...
著者Fu, L, Wu, Y, Bi, Y, Zhang, S, Lv, X, Qi, J, Li, Y, Lu, X, Yan, J, Gao, G.F, Li, X.
登録日2016-05-15
公開日2016-06-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
5JWA
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BU of 5jwa by Molmil
the structure of malaria PfNDH2
分子名称: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, ...
著者Yu, Y, Yang, Y.Q, Li, X.L, Yu, J, Ge, J.P, Li, J, Rao, Y, Yang, M.J.
登録日2016-05-11
公開日2017-03-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.162 Å)
主引用文献Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria
J. Med. Chem., 60, 2017
8WYI
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BU of 8wyi by Molmil
T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC
分子名称: Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ...
著者Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
登録日2023-10-31
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024
8WY0
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BU of 8wy0 by Molmil
T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A
分子名称: CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ...
著者Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
登録日2023-10-30
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024
8YC0
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BU of 8yc0 by Molmil
T cell receptor V delta2 V gamma9 in GDN
分子名称: CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ...
著者Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
登録日2024-02-17
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (4.12 Å)
主引用文献Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024
8WXE
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BU of 8wxe by Molmil
Vgamma5Vdelta1 EH TCR-CD3 complex
分子名称: CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ...
著者Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
登録日2023-10-28
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024

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件を2024-06-12に公開中

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