8W4U
human KCNQ2-CaM in complex with PIP2 and HN37
Summary for 8W4U
Entry DOI | 10.2210/pdb8w4u/pdb |
EMDB information | 37270 |
Descriptor | Potassium voltage-gated channel subfamily KQT member 2, Calmodulin-1, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate, ... (4 entities in total) |
Functional Keywords | potassium voltage-gated channel, hn37, pip2, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 366269.26 |
Authors | |
Primary citation | Ma, D.,Zheng, Y.,Li, X.,Zhou, X.,Yang, Z.,Zhang, Y.,Wang, L.,Zhang, W.,Fang, J.,Zhao, G.,Hou, P.,Nan, F.,Yang, W.,Su, N.,Gao, Z.,Guo, J. Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14:6632-6632, 2023 Cited by PubMed: 37857637DOI: 10.1038/s41467-023-42416-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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