5JWA
the structure of malaria PfNDH2
Summary for 5JWA
Entry DOI | 10.2210/pdb5jwa/pdb |
Related | 5JWA 5JWC |
Descriptor | NADH dehydrogenase, putative, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | pfndh2, fad, membrane protein-inhibitor complex, membrane protein/inhibitor |
Biological source | Plasmodium falciparum (isolate 3D7) |
Total number of polymer chains | 2 |
Total formula weight | 125187.55 |
Authors | Yu, Y.,Yang, Y.Q.,Li, X.L.,Yu, J.,Ge, J.P.,Li, J.,Rao, Y.,Yang, M.J. (deposition date: 2016-05-11, release date: 2017-03-22, Last modification date: 2023-11-08) |
Primary citation | Yang, Y.,Yu, Y.,Li, X.,Li, J.,Wu, Y.,Yu, J.,Ge, J.,Huang, Z.,Jiang, L.,Rao, Y.,Yang, M. Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria J. Med. Chem., 60:1994-2005, 2017 Cited by PubMed: 28195463DOI: 10.1021/acs.jmedchem.6b01733 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.162 Å) |
Structure validation
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