7TBY

The structure of human ABCA1 in nanodisc

Summary for 7TBY

Entry DOI	10.2210/pdb7tby/pdb
EMDB information	25800 25801 25802 25803
Descriptor	ATP-binding cassette, sub-family A (ABC1), member 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	hdl, cholesterol, tangier disease, abc transporter, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	257819.28
Authors	Sun, Y.,Li, X. (deposition date: 2021-12-22, release date: 2022-01-26, Last modification date: 2023-05-24)
Primary citation	Sun, Y.,Li, X. Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states. Nat Cardiovasc Res, 1:238-245, 2022 Cited by PubMed: 37181814 DOI: 10.1038/s44161-022-00022-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation