8XJO

U46619 bound Thromboxane A2 receptor-Gq Protein Complex

Summary for 8XJO

Entry DOI	10.2210/pdb8xjo/pdb
EMDB information	38403
Descriptor	Engineered miniGq, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	cryo-em, complex, signaling protein, membrane protein
Biological source	synthetic construct More
Total number of polymer chains	5
Total formula weight	165756.68
Authors	Zhang, X.,Li, X.,Liu, G.,Gong, W. (deposition date: 2023-12-21, release date: 2024-02-28, Last modification date: 2024-03-20)
Primary citation	Li, X.,Zhang, X.,Wen, X.,Zhang, D.,Qu, C.,Miao, X.,Zhang, W.,Zhang, R.,Liu, G.,Xiao, P.,Sun, J.P.,Gong, W. Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43:113893-113893, 2024 Cited by PubMed: 38446662 DOI: 10.1016/j.celrep.2024.113893 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.11 Å)

Structure validation