6E7Y

cryo-EM structure of human TRPML1 with PI45P2

Summary for 6E7Y

Entry DOI	10.2210/pdb6e7y/pdb
EMDB information	9001
Descriptor	Mucolipin-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (2 entities in total)
Functional Keywords	human trpml1, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	263326.25
Authors	Schmiege, P.,Li, X. (deposition date: 2018-07-27, release date: 2018-11-28)
Primary citation	Fine, M.,Schmiege, P.,Li, X. Structural basis for PtdInsP2-mediated human TRPML1 regulation. Nat Commun, 9:4192-4192, 2018 Cited by PubMed: 30305615 DOI: 10.1038/s41467-018-06493-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.57 Å)

Structure validation