6E7Y

cryo-EM structure of human TRPML1 with PI45P2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Mucolipin-1	polymer	580	65085.0	4	UniProt (Q9GZU1) Pfam (PF21381) Pfam (PF08016)	Homo sapiens (Human)	ML1,MG-2,Mucolipidin,Transient receptor potential channel mucolipin 1,TRPML1
2	E, F, G, H (A, B, C, D)	[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate	non-polymer		746.6	4	Chemie (PIO)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	260340.0
Non-Polymers*	Number of molecules	4
	Total formula weight	2986.3
All*	Total formula weight	263326.2

*Water molecules are not included.