2UZC
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![BU of 2uzc by Molmil](/molmil-images/mine/2uzc) | Structure of human PDLIM5 in complex with the C-terminal peptide of human alpha-actinin-1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PDZ AND LIM DOMAIN 5 | Authors: | Bunkoczi, G, Elkins, J, Salah, E, Burgess-Brown, N, Papagrigoriou, E, Pike, A.C.W, Turnbull, A, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Weigelt, J, Doyle, D. | Deposit date: | 2007-04-27 | Release date: | 2007-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms. Protein Sci., 19, 2010
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6BNK
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![BU of 6bnk by Molmil](/molmil-images/mine/6bnk) | Crystal structure of TCR-MHC-like molecule | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Le Nours, J, Rossjohn, J. | Deposit date: | 2017-11-16 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chem Biol, 25, 2018
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6JJJ
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6JCL
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![BU of 6jcl by Molmil](/molmil-images/mine/6jcl) | Crystal structure of cofactor-bound Rv0187 from MTB | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Probable O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Kim, J, Lee, S. | Deposit date: | 2019-01-29 | Release date: | 2019-12-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.644 Å) | Cite: | Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis. Sci Rep, 9, 2019
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4AP6
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![BU of 4ap6 by Molmil](/molmil-images/mine/4ap6) | Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ... | Authors: | Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H. | Deposit date: | 2012-03-30 | Release date: | 2012-08-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.401 Å) | Cite: | Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J., 31, 2012
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6JLQ
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![BU of 6jlq by Molmil](/molmil-images/mine/6jlq) | Crystal structure of human USP46-WDR48-WDR20 complex | Descriptor: | GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ... | Authors: | Zhu, H, Zhang, T, Ding, J. | Deposit date: | 2019-03-06 | Release date: | 2019-07-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.101 Å) | Cite: | Structural insights into the activation of USP46 by WDR48 and WDR20. Cell Discov, 5, 2019
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7WZ6
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![BU of 7wz6 by Molmil](/molmil-images/mine/7wz6) | Crystal structure of MyoD-E47 | Descriptor: | Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1 | Authors: | Zhong, J, Huang, Y, Ma, J. | Deposit date: | 2022-02-17 | Release date: | 2022-06-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis of the bHLH domains of MyoD-E47 heterodimer. Biochem.Biophys.Res.Commun., 621, 2022
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2KRC
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![BU of 2krc by Molmil](/molmil-images/mine/2krc) | Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase | Descriptor: | DNA-directed RNA polymerase subunit delta | Authors: | Motackova, V, Sanderova, H, Zidek, L, Novacek, J, Padrta, P, Svenkova, A, Jonak, J, Krasny, L, Sklenar, V. | Deposit date: | 2009-12-16 | Release date: | 2010-04-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase and its classification based on structural homologs Proteins, 78, 2010
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4QNV
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![BU of 4qnv by Molmil](/molmil-images/mine/4qnv) | Crystal structure of Cx-SAM bound CmoB from E. coli in P6122 | Descriptor: | (2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio] -2-ammoniobutanoate, PHOSPHATE ION, tRNA (mo5U34)-methyltransferase | Authors: | Kim, J, Toro, R, Bhosle, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-06-18 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification. Nucleic Acids Res., 43, 2015
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4QBO
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![BU of 4qbo by Molmil](/molmil-images/mine/4qbo) | VRR_NUC domain | Descriptor: | MAGNESIUM ION, Nuclease | Authors: | Smerdon, S.J, Pennell, S, Li, J. | Deposit date: | 2014-05-08 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain. Cell Rep, 8, 2014
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4A2J
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![BU of 4a2j by Molmil](/molmil-images/mine/4a2j) | PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids | Descriptor: | 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, PROGESTERONE RECEPTOR, SULFATE ION | Authors: | Lusher, S.J, Raaijmakers, H.C.A, Bosch, R, Vu-Pham, D, McGuire, R, Oubrie, A, de Vlieg, J. | Deposit date: | 2011-09-27 | Release date: | 2012-04-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of progesterone receptor ligand binding domain in its agonist state reveal differing mechanisms for mixed profiles of 11 beta-substituted steroids. J. Biol. Chem., 287, 2012
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6JPB
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![BU of 6jpb by Molmil](/molmil-images/mine/6jpb) | Rabbit Cav1.1-Diltiazem Complex | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhao, Y, Huang, G, Wu, J, Yan, N. | Deposit date: | 2019-03-26 | Release date: | 2019-06-12 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel. Cell, 177, 2019
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4QEO
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![BU of 4qeo by Molmil](/molmil-images/mine/4qeo) | crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH | Descriptor: | DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ... | Authors: | Du, J, Li, S, Patel, D.J. | Deposit date: | 2014-05-17 | Release date: | 2014-07-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4QCI
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![BU of 4qci by Molmil](/molmil-images/mine/4qci) | PDGF-B blocking antibody bound to PDGF-BB | Descriptor: | Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain | Authors: | Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G. | Deposit date: | 2014-05-12 | Release date: | 2015-03-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta. Biochemistry, 54, 2015
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3FWH
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![BU of 3fwh by Molmil](/molmil-images/mine/3fwh) | Structure of haloalkane dehalogenase mutant Dha15 (I135F/C176Y) from Rhodococcus rhodochrous | Descriptor: | ACETATE ION, CHLORIDE ION, Haloalkane dehalogenase, ... | Authors: | Gavira, J.A, Stsiapanava, A, Kuty, M, Dohnalek, J, Lapkouski, M, Kuta Smatanova, I. | Deposit date: | 2009-01-18 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Atomic resolution studies of haloalkane dehalogenases DhaA04, DhaA14 and DhaA15 with engineered access tunnels. Acta Crystallogr.,Sect.D, 66, 2010
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4A39
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![BU of 4a39 by Molmil](/molmil-images/mine/4a39) | Metallo-carboxypeptidase from Pseudomonas Aeruginosa in complex with (2-guanidinoethylmercapto)succinic acid | Descriptor: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, METALLO-CARBOXYPEPTIDASE, ZINC ION | Authors: | Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D. | Deposit date: | 2011-09-30 | Release date: | 2012-05-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps. Faseb J., 26, 2012
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3OAI
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![BU of 3oai by Molmil](/molmil-images/mine/3oai) | Crystal structure of the extra-cellular domain of human myelin protein zero | Descriptor: | Maltose-binding periplasmic protein, Myelin protein P0, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Liu, Z, Wang, Y, Brunzelle, J, Kovari, I.A, Sohi, J, Kamholz, J, Kovari, L.C. | Deposit date: | 2010-08-05 | Release date: | 2011-12-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the extracellular domain of human myelin protein zero. Proteins, 80, 2012
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6CEL
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![BU of 6cel by Molmil](/molmil-images/mine/6cel) | CBH1 (E212Q) CELLOPENTAOSE COMPLEX | Descriptor: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... | Authors: | Divne, C, Stahlberg, J, Jones, T.A. | Deposit date: | 1997-09-24 | Release date: | 1997-12-24 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 275, 1998
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6VPZ
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![BU of 6vpz by Molmil](/molmil-images/mine/6vpz) | HLA-B*27:05 presenting an HIV-1 11mer peptide | Descriptor: | 11-mer peptide, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N. | Deposit date: | 2020-02-04 | Release date: | 2021-02-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Epitope length variants balance protective immune responses and viral escape in HIV-1 infection Cell Rep, 38, 2022
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5N8J
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![BU of 5n8j by Molmil](/molmil-images/mine/5n8j) | CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE D-amino acid containing peptide GyGlanvdessG | Descriptor: | GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY, ISOPROPYL ALCOHOL, Streptavidin | Authors: | Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J. | Deposit date: | 2017-02-23 | Release date: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target. Sci Rep, 7, 2017
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4BP3
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![BU of 4bp3 by Molmil](/molmil-images/mine/4bp3) | Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with DECARBOXYLATED S-ADENOSYLMETHIONINE5' AND 4- METHYLANILINE | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-METHYLANILINE, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ... | Authors: | Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Persson, L. | Deposit date: | 2013-05-23 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design Acta Crystallogr.,Sect.D, 71, 2015
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1RDQ
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![BU of 1rdq by Molmil](/molmil-images/mine/1rdq) | Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Yang, J, Ten Eyck, L.F, Xuong, N.H, Taylor, S.S. | Deposit date: | 2003-11-05 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism. J.Mol.Biol., 336, 2004
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5XOT
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![BU of 5xot by Molmil](/molmil-images/mine/5xot) | Crystal structure of pHLA-B35 in complex with TU55 T cell receptor | Descriptor: | An HIV reverse transcriptase epitope, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2017-05-31 | Release date: | 2017-06-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.787 Å) | Cite: | Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs. J. Virol., 91, 2017
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3WL5
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![BU of 3wl5 by Molmil](/molmil-images/mine/3wl5) | Crystal structure of pOPH S172C | Descriptor: | CITRIC ACID, Oxidized polyvinyl alcohol hydrolase | Authors: | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chan, H.C, Ren, F.F, Jia, D.X, Wang, A.H.-J, Guo, R.T, Chen, J, Du, G.C. | Deposit date: | 2013-11-07 | Release date: | 2014-09-24 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights into enzymatic degradation of oxidized polyvinyl alcohol Chembiochem, 15, 2014
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6CFJ
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![BU of 6cfj by Molmil](/molmil-images/mine/6cfj) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with histidyl-CAM and bound to mRNA and A-, P-, and E-site tRNAs at 2.8A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S. | Deposit date: | 2018-02-15 | Release date: | 2018-03-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome. J. Mol. Biol., 430, 2018
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