6BNK

Crystal structure of TCR-MHC-like molecule

Summary for 6BNK

• Entry DOI: 10.2210/pdb6bnk/pdb
• Descriptor: Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, NKT Valpha14 (MOUSE) - 2C12 TCR - Hybrid mouse variable and human constant domains, ... (8 entities in total)
• Functional Keywords: lipids cancer, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 8
• Total formula weight: 195881.33

Authors

Le Nours, J.,Rossjohn, J. (deposition date: 2017-11-16, release date: 2018-04-04, Last modification date: 2023-10-04)

• Primary citation: Chennamadhavuni, D.,Saavedra-Avila, N.A.,Carreno, L.J.,Guberman-Pfeffer, M.J.,Arora, P.,Yongqing, T.,Koay, H.F.,Godfrey, D.I.,Keshipeddy, S.,Richardson, S.K.,Sundararaj, S.,Lo, J.H.,Wen, X.,Gascon, J.A.,Yuan, W.,Rossjohn, J.,Le Nours, J.,Porcelli, S.A.,Howell, A.R.; Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.; Cell Chem Biol, 25:571-, 2018; PubMed: 29576533; DOI: 10.1016/j.chembiol.2018.02.009

Experimental method

X-RAY DIFFRACTION (3.2 Å)