crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH

Summary for 4QEO

Related4QEN 4QEP
DescriptorHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4, DNA 5'-GGTACT(5CM)ATCAGTAT-3', DNA 5'-ACTGATGAGTACCAT-3', ... (7 entities in total)
Functional Keywordssra, set, histone methylation, methylated dna, methylation, transcription-dna complex, transcription/dna
Biological sourceArabidopsis thaliana (mouse-ear cress,thale-cress)
Cellular locationNucleus Q8GZB6
Total number of polymer chains4
Total molecular weight71089.67
Du, J.,Li, S.,Patel, D.J. (deposition date: 2014-05-17, release date: 2014-07-30, Last modification date: 2014-08-20)
Primary citation
Du, J.,Johnson, L.M.,Groth, M.,Feng, S.,Hale, C.J.,Li, S.,Vashisht, A.A.,Gallego-Bartolome, J.,Wohlschlegel, J.A.,Patel, D.J.,Jacobsen, S.E.
Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55:495-504, 2014
PubMed: 25018018 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2014.06.009
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.224130.9%8.0%11.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution