crystal structure of KRYPTONITE in complex with mCHH DNA and SAH

Summary for 4QEN

Related4QEO 4QEP
DescriptorHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4, DNA (5'-D(*GP*GP*TP*AP*CP*TP*(5CM)P*AP*TP*CP*AP*GP*TP*AP*T)-3'), DNA (5'-D(*AP*CP*TP*GP*AP*TP*GP*AP*GP*TP*AP*CP*CP*AP*T)-3'), ... (6 entities in total)
Functional Keywordssra, set, histone methylation, methylated dna, transcription-dna complex, transcription/dna
Biological sourceArabidopsis thaliana (mouse-ear cress,thale-cress)
Cellular locationNucleus Q8GZB6
Total number of polymer chains3
Total molecular weight69523.88
Du, J.,Li, S.,Patel, D.J. (deposition date: 2014-05-17, release date: 2014-07-30, Last modification date: 2014-08-20)
Primary citation
Du, J.,Johnson, L.M.,Groth, M.,Feng, S.,Hale, C.J.,Li, S.,Vashisht, A.A.,Gallego-Bartolome, J.,Wohlschlegel, J.A.,Patel, D.J.,Jacobsen, S.E.
Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55:495-504, 2014
PubMed: 25018018 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2014.06.009
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21750.4%4.6%7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-05