4QEO
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 | polymer | 533 | 59686.8 | 1 | UniProt (Q8GZB6) Pfam (PF02182) Pfam (PF05033) Pfam (PF00856) | Arabidopsis thaliana (mouse-ear cress thale-cress) | Histone H3-K9 methyltransferase 4, H3-K9-HMTase 4, Protein KRYPTONITE, Protein SET DOMAIN GROUP 33, Suppressor of variegation 3-9 homolog protein 4, Su(var)3-9 homolog protein 4 |
| 2 | B (C) | DNA 5'-GGTACT(5CM)ATCAGTAT-3' | polymer | 15 | 4598.0 | 1 | Synthetic construct | ||
| 3 | C (D) | DNA 5'-ACTGATGAGTACCAT-3' | polymer | 15 | 4593.0 | 1 | Synthetic construct | ||
| 4 | D (P) | Histone H3 | polymer | 15 | 1565.8 | 1 | UniProt (Q92133) UniProt (by SIFTS) (P84233) | Xenopus laevis | |
| 5 | E (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 6 | F, G, H, I (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 7 | J, K, L, M (A, C, D, P) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A: 93 - 624 (UniProt: Q8GZB6)
| PDB | External Database | Details |
|---|---|---|
| Ser 92 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 70443.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 646.0 | |
| All* | Total formula weight | 71089.7 |
