4BP3

Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with DECARBOXYLATED S-ADENOSYLMETHIONINE5' AND 4- METHYLANILINE

Summary for 4BP3

Entry DOI	10.2210/pdb4bp3/pdb
Related	4BP1
Descriptor	SPERMIDINE SYNTHASE, 4-METHYLANILINE, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ... (6 entities in total)
Functional Keywords	transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold
Biological source	PLASMODIUM FALCIPARUM
Total number of polymer chains	3
Total formula weight	98650.95
Authors	Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Persson, L. (deposition date: 2013-05-23, release date: 2014-06-25, Last modification date: 2023-12-20)
Primary citation	Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S. Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design Acta Crystallogr.,Sect.D, 71:484-, 2015 Cited by PubMed: 25760598 DOI: 10.1107/S1399004714027011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation