5LEG
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![BU of 5leg by Molmil](/molmil-images/mine/5leg) | Structure of the bacterial sex F pilus (pED208) | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, Pilin | Authors: | Costa, T.R.D, Ilangovan, I, Ukleja, M, Redzej, A, Santini, J.M, Smith, T.K, Egelman, E.H, Waksman, G. | Deposit date: | 2016-06-29 | Release date: | 2016-09-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex. Cell, 166, 2016
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5LER
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![BU of 5ler by Molmil](/molmil-images/mine/5ler) | Structure of the bacterial sex F pilus (13.2 Angstrom rise) | Descriptor: | Pilin, [(2~{S})-3-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-2-hexadec-9-enoyloxy-propyl] hexadecanoate | Authors: | Costa, T.R.D, Ilangovan, I, Ukleja, M, Redzej, A, Santini, J.M, Smith, T.K, Egelman, E.H, Waksman, G. | Deposit date: | 2016-06-30 | Release date: | 2016-11-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex. Cell, 166, 2016
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5LFB
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![BU of 5lfb by Molmil](/molmil-images/mine/5lfb) | Structure of the bacterial sex F pilus (12.5 Angstrom rise) | Descriptor: | Pilin, [(2~{S})-3-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-2-hexadec-9-enoyloxy-propyl] hexadecanoate | Authors: | Costa, T.R.D, Ilangovan, I, Ukleja, M, Redzej, A, Santini, J.M, Smith, T.K, Egelman, E.H, Waksman, G. | Deposit date: | 2016-06-30 | Release date: | 2016-11-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex. Cell, 166, 2016
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8OJJ
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![BU of 8ojj by Molmil](/molmil-images/mine/8ojj) | Cryo-EM structure of the DnaD-NTD tetramer | Descriptor: | DNA replication protein DnaD | Authors: | Winterhalter, C, Pelliciari, S, Cronin, N, Costa, T.R.D, Murray, H, Ilangovan, A. | Deposit date: | 2023-03-24 | Release date: | 2023-05-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (5.47 Å) | Cite: | The DNA replication initiation protein DnaD recognises a specific strand of the Bacillus subtilis chromosome origin. Nucleic Acids Res., 51, 2023
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5JQH
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![BU of 5jqh by Molmil](/molmil-images/mine/5jqh) | Structure of beta2 adrenoceptor bound to carazolol and inactive-state stabilizing nanobody, Nb60 | Descriptor: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, CHOLESTEROL, Endolysin,Beta-2 adrenergic receptor, ... | Authors: | Staus, D.P, Strachan, R.T, Manglik, A, Pani, B, Kahsai, A.W, Kim, T.H, Wingler, L.M, Ahn, S, Chatterjee, A, Masoudi, A, Kruse, A.C, Pardon, E, Steyaert, J, Weis, W.I, Prosser, R.S, Kobilka, B.K, Costa, T, Lefkowitz, R.J. | Deposit date: | 2016-05-05 | Release date: | 2016-07-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation. Nature, 535, 2016
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7T34
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![BU of 7t34 by Molmil](/molmil-images/mine/7t34) | |
5OH0
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![BU of 5oh0 by Molmil](/molmil-images/mine/5oh0) | The Cryo-Electron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Hospenthal, M.K, Costa, T.R.D, Redzej, A, Waksman, G. | Deposit date: | 2017-07-13 | Release date: | 2017-11-22 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod. Structure, 25, 2017
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7OKO
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![BU of 7oko by Molmil](/molmil-images/mine/7oko) | |
6P90
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![BU of 6p90 by Molmil](/molmil-images/mine/6p90) | Crystal structure of PaDHDPS2-H56Q mutant | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, GLYCEROL | Authors: | Impey, R.E, Panjikar, S, Hall, C.J, Bock, L.J, Sutton, J.M, Perugini, M.A, Soares da Costa, T.P. | Deposit date: | 2019-06-08 | Release date: | 2019-08-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation. Febs J., 287, 2020
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4DQ2
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![BU of 4dq2 by Molmil](/molmil-images/mine/4dq2) | Structure of staphylococcus aureus biotin protein ligase in complex with biotinol-5'-amp | Descriptor: | ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, Biotin-[acetyl-CoA-carboxylase] ligase | Authors: | Wilce, M, Yap, M, Pendini, N, Soares de Costa, T, Polyak, S, Tieu, W, Booker, G, Wallace, J. | Deposit date: | 2012-02-14 | Release date: | 2012-04-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
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6GYB
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![BU of 6gyb by Molmil](/molmil-images/mine/6gyb) | Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri | Descriptor: | VirB10 protein, VirB7, VirB9 protein | Authors: | Sgro, G.G, Costa, T.R.D, Farah, C.S, Waksman, G. | Deposit date: | 2018-06-28 | Release date: | 2018-10-24 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri. Nat Microbiol, 3, 2018
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7KHW
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![BU of 7khw by Molmil](/molmil-images/mine/7khw) | |
3I7S
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![BU of 3i7s by Molmil](/molmil-images/mine/3i7s) | Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site. | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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7OKN
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![BU of 7okn by Molmil](/molmil-images/mine/7okn) | |
5SXO
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![BU of 5sxo by Molmil](/molmil-images/mine/5sxo) | |
3I7Q
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![BU of 3i7q by Molmil](/molmil-images/mine/3i7q) | Dihydrodipicolinate synthase mutant - K161A | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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7QS8
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![BU of 7qs8 by Molmil](/molmil-images/mine/7qs8) | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | Descriptor: | Protein Tax-1, Protein scribble homolog | Authors: | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | Deposit date: | 2022-01-13 | Release date: | 2022-09-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
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7QRS
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![BU of 7qrs by Molmil](/molmil-images/mine/7qrs) | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | Descriptor: | ACETATE ION, GLYCEROL, Protein Tax-1, ... | Authors: | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | Deposit date: | 2022-01-12 | Release date: | 2022-09-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
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7QRT
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![BU of 7qrt by Molmil](/molmil-images/mine/7qrt) | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | Descriptor: | CHLORIDE ION, Protein Tax-1, Protein scribble homolog, ... | Authors: | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M, Maddumage, J.C. | Deposit date: | 2022-01-12 | Release date: | 2022-09-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
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3I7R
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![BU of 3i7r by Molmil](/molmil-images/mine/3i7r) | Dihydrodipicolinate synthase - K161R | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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4HA8
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![BU of 4ha8 by Molmil](/molmil-images/mine/4ha8) | Structure of Staphylococcus aureus biotin protein ligase in complex with biotin acetylene | Descriptor: | (3aS,4S,6aR)-4-(hex-5-yn-1-yl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one, Biotin-[acetyl-CoA-carboxylase] ligase | Authors: | Yap, M, Wilce, M, Polyak, S, Soares da Costa, T, Tieu, W. | Deposit date: | 2012-09-25 | Release date: | 2013-10-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of Staphylococcus aureus biotin protein ligase in complex with biotin acetylene To be Published
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7MDS
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![BU of 7mds by Molmil](/molmil-images/mine/7mds) | Crystal structure of AtDHDPS1 in complex with MBDTA-2 | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ... | Authors: | Hall, C.J, Soares da Costa, T.P, Panjikar, S. | Deposit date: | 2021-04-06 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants. Elife, 10, 2021
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5KT0
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![BU of 5kt0 by Molmil](/molmil-images/mine/5kt0) | Dihydrodipicolinate reductase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis. | Descriptor: | 4-hydroxy-tetrahydrodipicolinate reductase, MAGNESIUM ION | Authors: | Christensen, J.B, Soares da Costa, T.P, Faou, P, Pearce, F.G, Panjikar, S, Perugini, M.A. | Deposit date: | 2016-07-10 | Release date: | 2016-09-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Dihydrodipicolinate Reductase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis. To Be Published
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6UE0
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![BU of 6ue0 by Molmil](/molmil-images/mine/6ue0) | Crystal structure of dihydrodipicolinate synthase from Klebsiella pneumoniae bound to pyruvate | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, SULFATE ION | Authors: | Impey, R.E, Lee, M, Hawkins, D.A, Sutton, J.M, Panjikar, S, Perugini, M.A, Soares da Costa, T.P. | Deposit date: | 2019-09-20 | Release date: | 2020-02-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | Mis-annotations of a promising antibiotic target in high-priority gram-negative pathogens. Febs Lett., 594, 2020
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