7MDS

Crystal structure of AtDHDPS1 in complex with MBDTA-2

Summary for 7MDS

Entry DOI	10.2210/pdb7mds/pdb
Descriptor	4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, {(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetic acid, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	herbicide, lysine biosynthesis, biosynthetic protein, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	2
Total formula weight	76446.94
Authors	Hall, C.J.,Soares da Costa, T.P.,Panjikar, S. (deposition date: 2021-04-06, release date: 2021-08-04, Last modification date: 2023-10-18)
Primary citation	Soares da Costa, T.P.,Hall, C.J.,Panjikar, S.,Wyllie, J.A.,Christoff, R.M.,Bayat, S.,Hulett, M.D.,Abbott, B.M.,Gendall, A.R.,Perugini, M.A. Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants. Elife, 10:-, 2021 Cited by PubMed: 34313586 DOI: 10.7554/eLife.69444 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.295 Å)

Structure validation