7QS8

Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1

Summary for 7QS8

Entry DOI	10.2210/pdb7qs8/pdb
Descriptor	Protein scribble homolog, Protein Tax-1 (3 entities in total)
Functional Keywords	human t lymphotrophic virus-1, htlv-1, cell polarity, isothermal titration calorimetry, tax1, pdz, scribble, viral protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	21726.76
Authors	Javorsky, A.,Soares da Costa, T.P.,Mackie, E.R.,Humbert, P.O.,Kvansakul, M. (deposition date: 2022-01-13, release date: 2022-09-07, Last modification date: 2024-02-07)
Primary citation	Javorsky, A.,Maddumage, J.C.,Mackie, E.R.R.,Soares da Costa, T.P.,Humbert, P.O.,Kvansakul, M. Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290:974-987, 2023 Cited by PubMed: 36029163 DOI: 10.1111/febs.16607 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation