3I7S
Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site.
Summary for 3I7S
Entry DOI | 10.2210/pdb3i7s/pdb |
Related | 3I7Q 3I7R |
Descriptor | Dihydrodipicolinate synthase, GLYCEROL, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | dihydrodipicolinate synthyase, lysine biosynthesis, amino-acid biosynthesis, diaminopimelate biosynthesis, lyase, schiff base |
Biological source | Escherichia coli K-12 |
Cellular location | Cytoplasm: P0A6L2 |
Total number of polymer chains | 2 |
Total formula weight | 64098.27 |
Authors | Dobson, R.C.J.,Jameson, G.B.,Gerrard, J.A.,Soares da Costa, T.P. (deposition date: 2009-07-08, release date: 2010-04-14, Last modification date: 2023-11-15) |
Primary citation | Soares da Costa, T.P.,Muscroft-Taylor, A.C.,Dobson, R.C.,Devenish, S.R.,Jameson, G.B.,Gerrard, J.A. How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92:837-845, 2010 Cited by PubMed: 20353808DOI: 10.1016/j.biochi.2010.03.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report