6P90

Crystal structure of PaDHDPS2-H56Q mutant

Summary for 6P90

Entry DOI	10.2210/pdb6p90/pdb
Descriptor	4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	allosteric regulation, antibiotic resistance, diaminopimelate, 4-hydroxy-tetrahydrodipicolinate synthase, lysine biosynthesis, structural protein
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	63205.68
Authors	Impey, R.E.,Panjikar, S.,Hall, C.J.,Bock, L.J.,Sutton, J.M.,Perugini, M.A.,Soares da Costa, T.P. (deposition date: 2019-06-08, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citation	Impey, R.E.,Panjikar, S.,Hall, C.J.,Bock, L.J.,Sutton, J.M.,Perugini, M.A.,Soares da Costa, T.P. Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation. Febs J., 287:386-400, 2020 Cited by PubMed: 31330085 DOI: 10.1111/febs.15014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation