6UE0

Crystal structure of dihydrodipicolinate synthase from Klebsiella pneumoniae bound to pyruvate

This is a large structure.

Summary for 6UE0

Descriptor4-hydroxy-tetrahydrodipicolinate synthase, SULFATE ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsdhdps, lysine biosynthesis, tetramer, lyase
Biological sourceKlebsiella pneumoniae
Total number of polymer chains2
Total molecular weight70038.5
Authors
Impey, R.E.,Lee, M.,Hawkins, D.A.,Sutton, J.M.,Panjikar, S.,Perugini, M.A.,Soares da Costa, T.P. (deposition date: 2019-09-20, release date: 2020-02-05)
Primary citation
Impey, R.E.,Lee, M.,Hawkins, D.A.,Sutton, J.M.,Panjikar, S.,Perugini, M.A.,Soares da Costa, T.P.
Mis-annotations of a promising antibiotic target in high-priority gram-negative pathogens.
Febs Lett., 2020
PubMed: 31943170 (PDB entries with the same primary citation)
DOI: 10.1002/1873-3468.13733
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.892 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20720 0.4% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload