5GXJ
| Zika Virus NS2B-NS3 protease | 分子名称: | FLAVIVIRUS_NS2B,LINKER,Peptidase S7 | 著者 | Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K. | 登録日 | 2016-09-18 | 公開日 | 2017-05-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Viral protease activation mechanism To Be Published
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1C8J
| CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F) | 分子名称: | CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Liu, Y, Jiang, F, Guo, Q, Chen, X, Jin, J, Sun, Y, Rao, Z. | 登録日 | 2000-05-31 | 公開日 | 2001-05-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F) To be Published
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4D8P
| Structural and functional studies of the trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) molecule | 分子名称: | GLYCEROL, HLA-DQA1 protein, Peptide from Gamma-gliadin,HLA class II histocompatibility antigen, ... | 著者 | Kim, C.-Y, Hotta, K, Mathews, I.I, Chen, X. | 登録日 | 2012-01-11 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule J.Biol.Chem., 287, 2012
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5H6X
| The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila | 分子名称: | GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION | 著者 | Zhang, N, Chen, X, Gong, X, Ge, H. | 登録日 | 2016-11-15 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila Crystals, 8, 2018
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4YIR
| Crystal structure of Rad4-Rad23 crosslinked to an undamaged DNA | 分子名称: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*G*GP*GP*GP*AP*TP*GP*TP*CP*GP*AP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*CP*GP*CP*TP*AP*CP*AP*A)-3'), DNA repair protein RAD4, ... | 著者 | Min, J.-H, Chen, X, Kim, Y. | 登録日 | 2015-03-02 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.0501 Å) | 主引用文献 | Kinetic gating mechanism of DNA damage recognition by Rad4/XPC. Nat Commun, 6, 2015
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1BF5
| TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX | 分子名称: | DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA | 著者 | Kuriyan, J, Zhao, Y, Chen, X, Vinkemeier, U, Jeruzalmi, D, Darnell Jr, J.E. | 登録日 | 1998-05-27 | 公開日 | 1998-08-12 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell(Cambridge,Mass.), 93, 1998
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6LS4
| A novel anti-tumor agent S-40 in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | 著者 | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | 登録日 | 2020-01-17 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Cancer Lett., 495, 2020
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6M4Q
| Cytochrome P450 monooxygenase StvP2 substrate-free structure | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | 登録日 | 2020-03-08 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
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2PFD
| Anisotropically refined structure of FTCD | 分子名称: | Formimidoyltransferase-cyclodeaminase | 著者 | Poon, B.K, Chen, X, Lu, M, Quiocho, F.A, Wang, Q, Ma, J. | 登録日 | 2007-04-04 | 公開日 | 2007-04-24 | 最終更新日 | 2011-08-10 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Anisotropically refined structure of FTCD To be Published
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6VDK
| CryoEM structure of HIV-1 conserved Intasome Core | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | 著者 | Li, M, Chen, X, Craigie, R. | 登録日 | 2019-12-27 | 公開日 | 2020-02-05 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
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3HFH
| Crystal structure of tandem FF domains | 分子名称: | Transcription elongation regulator 1 | 著者 | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | 登録日 | 2009-05-11 | 公開日 | 2009-08-18 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150. J.Mol.Biol., 393, 2009
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3K5K
| Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a | 分子名称: | 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, CHLORIDE ION, Histone-lysine N-methyltransferase, ... | 著者 | Dong, A, Wasney, G.A, Liu, F, Chen, X, Allali-Hassani, A, Senisterra, G, Chau, I, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Frye, S.V, Bochkarev, A, Brown, P.J, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) | 登録日 | 2009-10-07 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J.Med.Chem., 52, 2009
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3K6S
| Structure of integrin alphaXbeta2 ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | 登録日 | 2009-10-09 | 公開日 | 2010-01-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of an integrin with an alphaI domain, complement receptor type 4. Embo J., 29, 2010
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3DWA
| Crystal structure of the B-subunit of the AB5 toxin from E. coli | 分子名称: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | 登録日 | 2008-07-22 | 公開日 | 2008-11-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3DWP
| Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | 分子名称: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | 登録日 | 2008-07-22 | 公開日 | 2008-11-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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3K72
| Structure of integrin alphaX beta2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | 登録日 | 2009-10-11 | 公開日 | 2010-01-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structure of an integrin with an alphaI domain, complement receptor type 4. Embo J., 29, 2010
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3V6G
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3V78
| Crystal Structure of Transcriptional Regulator | 分子名称: | ETHIDIUM, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) | 著者 | Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. | 登録日 | 2011-12-20 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res., 40, 2012
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3K71
| Structure of integrin alphaX beta2 ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A. | 登録日 | 2009-10-11 | 公開日 | 2010-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | 主引用文献 | Structure of an integrin with an alphaI domain, complement receptor type 4. Embo J., 29, 2010
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3DWQ
| Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | 分子名称: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | 著者 | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | 登録日 | 2008-07-22 | 公開日 | 2008-11-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin Nature, 456, 2008
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6K2H
| structural characterization of mutated NreA protein in nitrate binding site from staphylococcus aureus. | 分子名称: | 1,2-ETHANEDIOL, NreA | 著者 | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | 登録日 | 2019-05-14 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
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6IZJ
| Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, NreA | 著者 | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | 登録日 | 2018-12-19 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
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2JQQ
| Solution structure of Saccharomyces cerevisiae conserved oligomeric Golgi subunit 2 protein (Cog2p) | 分子名称: | Conserved oligomeric Golgi complex subunit 2 | 著者 | Cavanaugh, L.F, Chen, X, Pelczer, I, Rizo, J, Hughson, F.M. | 登録日 | 2007-06-06 | 公開日 | 2007-06-19 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural analysis of conserved oligomeric Golgi complex subunit 2 J.Biol.Chem., 282, 2007
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2KVT
| solution NMR structure of yaiA from Escherichia Eoli. Northeast Structural Genomics Target ER244 | 分子名称: | Uncharacterized protein yaiA | 著者 | Tang, Y, Chen, X, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-03-28 | 公開日 | 2010-05-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | solution NMR structure of yaiA from Escherichia coli. Northeast Structural Genomics Target ER244 To be Published
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8HQP
| Crystal structure of AbHheG mutant from Acidimicrobiia bacterium | 分子名称: | AbHheG_m | 著者 | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | 登録日 | 2022-12-13 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides Acs Catalysis, 13, 2023
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