1BF5

TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX

Summary for 1BF5

DescriptorDNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA (3 entities in total)
Functional Keywordscomplex (sh2 domain-dna), sh2 domain, transcription factor, gene regulation-dna complex, gene regulation/dna
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  P42224
Total number of polymer chains3
Total molecular weight77688.49
Authors
Kuriyan, J.,Zhao, Y.,Chen, X.,Vinkemeier, U.,Jeruzalmi, D.,Darnell Jr., J.E. (deposition date: 1998-05-27, release date: 1998-08-12, Last modification date: 2018-03-07)
Primary citation
Chen, X.,Vinkemeier, U.,Zhao, Y.,Jeruzalmi, D.,Darnell Jr., J.E.,Kuriyan, J.
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell(Cambridge,Mass.), 93:827-839, 1998
PubMed: 9630226 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(00)81443-9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28751 5.9% 4.8% 5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02