1BF5

TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0007165	biological_process	signal transduction

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	97
Details	Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"28753426","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"ADP-ribosyl glutamic acid; by PARP14","evidences":[{"source":"PubMed","id":"27796300","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by JAK1, JAK2 or TYK2","evidences":[{"source":"PubMed","id":"17561467","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19088846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21135090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22065572","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26479788","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27796300","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28753426","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38621137","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7657660","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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