6M4Q

Cytochrome P450 monooxygenase StvP2 substrate-free structure

Summary for 6M4Q

• Entry DOI: 10.2210/pdb6m4q/pdb
• Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: p450 anti-mrsa streptovaricin c methylenedioxy bridge stvp2 substrate-free structure, antibiotic
• Biological source: Streptomyces spectabilis
• Total number of polymer chains: 1
• Total formula weight: 44467.84

Authors

Sun, G.,Hu, C.,Mei, Q.,Luo, M.,Chen, X.,Li, Z.,Liu, Y.,Deng, Z.,Zhang, Z.,Sun, Y. (deposition date: 2020-03-08, release date: 2020-08-12, Last modification date: 2023-11-29)

• Primary citation: Sun, G.,Hu, C.,Mei, Q.,Luo, M.,Chen, X.,Li, Z.,Liu, Y.,Deng, Z.,Zhang, Z.,Sun, Y.; Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis.; Nat Commun, 11:4501-4501, 2020; PubMed: 32908132; DOI: 10.1038/s41467-020-18336-5

Experimental method

X-RAY DIFFRACTION (1.35 Å)