6VDK

CryoEM structure of HIV-1 conserved Intasome Core

Summary for 6VDK

• Entry DOI: 10.2210/pdb6vdk/pdb
• Related: 6U8Q
• EMDB information: 20689 21151
• Descriptor: Integrase, DNA (27-MER), DNA (25-MER), ... (5 entities in total)
• Functional Keywords: site-specific recombination, retroviruses, integrase, integration, nucleoprotein complex, dna complex, integrase strand transfer inhibitor, transferase-dna complex, transferase/dna
• Biological source: Human immunodeficiency virus 1 (HIV-1); More
• Total number of polymer chains: 12
• Total formula weight: 352045.41

Authors

Li, M.,Chen, X.,Craigie, R. (deposition date: 2019-12-27, release date: 2020-02-05, Last modification date: 2024-03-06)

• Primary citation: Li, M.,Chen, X.,Wang, H.,Jurado, K.A.,Engelman, A.N.,Craigie, R.; A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies.; J.Mol.Biol., 432:2055-2066, 2020; PubMed: 32061936; DOI: 10.1016/j.jmb.2020.01.040

Experimental method

ELECTRON MICROSCOPY (4.5 Å)