6VDK

CryoEM structure of HIV-1 conserved Intasome Core

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008270	molecular_function	zinc ion binding
A	0015074	biological_process	DNA integration
B	0003676	molecular_function	nucleic acid binding
B	0008270	molecular_function	zinc ion binding
B	0015074	biological_process	DNA integration
C	0003676	molecular_function	nucleic acid binding
C	0008270	molecular_function	zinc ion binding
C	0015074	biological_process	DNA integration
D	0003676	molecular_function	nucleic acid binding
D	0008270	molecular_function	zinc ion binding
D	0015074	biological_process	DNA integration
I	0003676	molecular_function	nucleic acid binding
I	0008270	molecular_function	zinc ion binding
I	0015074	biological_process	DNA integration
J	0003676	molecular_function	nucleic acid binding
J	0008270	molecular_function	zinc ion binding
J	0015074	biological_process	DNA integration
M	0003676	molecular_function	nucleic acid binding
M	0008270	molecular_function	zinc ion binding
M	0015074	biological_process	DNA integration
P	0003676	molecular_function	nucleic acid binding
P	0008270	molecular_function	zinc ion binding
P	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 301

Chain	Residue
A	ASP64
A	CYS65
A	ASP116
A	DLU303

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 302

Chain	Residue
A	ASP64
A	GLU152
A	DLU303

---

site_id	AC3
Number of Residues	11
Details	binding site for residue DLU A 303

Chain	Residue
A	PRO145
A	GLN146
A	GLU152
A	MG301
A	MG302
G	DG18
H	DC20
H	DA21
P	ARG231
A	ASP64
A	ASP116

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG C 301

Chain	Residue
C	ASP64
C	ASP116
C	GLU152
C	MG302
C	DLU303

---

site_id	AC5
Number of Residues	4
Details	binding site for residue MG C 302

Chain	Residue
C	ASP64
C	GLU152
C	MG301
C	DLU303

---

site_id	AC6
Number of Residues	11
Details	binding site for residue DLU C 303

Chain	Residue
C	ASP64
C	ASP116
C	PRO145
C	GLN146
C	GLU152
C	MG301
C	MG302
E	DG18
F	DC20
F	DA21
M	ARG231

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	300
Details	Domain: {"description":"Integrase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00457","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	329
Details	DNA binding: {"description":"Integrase-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00506","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	164
Details	Zinc finger: {"description":"Integrase-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---