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1B2T
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BU of 1b2t by Molmil
SOLUTION STRUCTURE OF THE CX3C CHEMOKINE DOMAIN OF FRACTALKINE
分子名称: PROTEIN (FRACTALKINE)
著者Handel, T.M, Mizoue, L.S, Bazan, J.F, Johnson, E.C.
登録日1998-12-01
公開日1999-04-08
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1.
Biochemistry, 38, 1999
1I1J
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BU of 1i1j by Molmil
STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN: A MEMBER OF A NEW FAMILY OF SECRETED PROTEINS
分子名称: MELANOMA DERIVED GROWTH REGULATORY PROTEIN
著者Lougheed, J.C, Holton, J.M, Alber, T, Bazan, J.F, Handel, T.M.
登録日2001-02-02
公開日2001-05-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins.
Proc.Natl.Acad.Sci.USA, 98, 2001
1OZN
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BU of 1ozn by Molmil
1.5A Crystal Structure of the Nogo Receptor Ligand Binding Domain Reveals a Convergent Recognition Scaffold Mediating Inhibition of Myelination
分子名称: ACETIC ACID, Reticulon 4 receptor, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者He, X, Bazan, J.F, Park, J.B, McDermott, G, He, Z, Garcia, K.C.
登録日2003-04-09
公開日2003-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure of the Nogo Receptor Ectodomain. A Recognition module implicated in Myelin Inhibition.
Neuron, 38, 2003
3UCR
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BU of 3ucr by Molmil
Crystal structure of the immunoreceptor TIGIT IgV domain
分子名称: CHLORIDE ION, T cell immunoreceptor with Ig and ITIM domains
著者Yin, J.P, Stengel, K.F, Rouge, L, Bazan, J.F, Wiesmann, C.
登録日2011-10-27
公開日2012-03-14
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.627 Å)
主引用文献Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DKE
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BU of 4dke by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb1.1
分子名称: FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKF
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Crystal Structure of Human Interleukin-34 Bound to FAb2
分子名称: FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKD
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BU of 4dkd by Molmil
Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ...
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKC
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BU of 4dkc by Molmil
Crystal Structure of Human Interleukin-34
分子名称: Interleukin-34, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
3UDW
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BU of 3udw by Molmil
Crystal structure of the immunoreceptor TIGIT in complex with Poliovirus receptor (PVR/CD155/necl-5) D1 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, T cell immunoreceptor with Ig and ITIM domains
著者Rouge, L, Stengel, K.F, Yin, J.P, Bazan, F.J, Wiesmann, C.
登録日2011-10-28
公開日2012-03-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Proc.Natl.Acad.Sci.USA, 109, 2012
2KJX
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BU of 2kjx by Molmil
Solution structure of the extracellular domain of JTB
分子名称: Jumping translocation breakpoint protein
著者Rousseau, F, Lingel, A, Pan, B, Fairbrother, W.J, Bazan, F.
登録日2009-06-10
公開日2010-08-11
最終更新日2012-04-18
実験手法SOLUTION NMR
主引用文献The structure of the extracellular domain of the jumping translocation breakpoint protein reveals a variation of the midkine fold.
J.Mol.Biol., 415, 2012
7ZG0
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BU of 7zg0 by Molmil
Murine IL-27 in complex with IL-27Ra and a non-competing Nb
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
著者Skladanowska, K, Bloch, Y, Savvides, S.N.
登録日2022-04-01
公開日2022-11-02
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
7ZXK
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BU of 7zxk by Molmil
Human IL-27 in complex with neutralizing SRF388 FAb fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ...
著者Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N.
登録日2022-05-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
3V42
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BU of 3v42 by Molmil
Crystal structure of renal tumor suppressor protein, folliculin
分子名称: Folliculin
著者Nookala, R.K, Chirgadze, D.Y, Blundell, T.L.
登録日2011-12-14
公開日2012-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.
Open Biol, 2, 2012
7NX2
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BU of 7nx2 by Molmil
Unbound antigen-binding fragment (FAb) 324
分子名称: FAb 324 Heavy Chain, FAb 324 Light Chain, SULFATE ION
著者De Munck, S, Savvides, S.N.
登録日2021-03-17
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
7NX3
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BU of 7nx3 by Molmil
Crystal structure of ALK in complex with Fab324
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor, Fab324 HeavyChain, ...
著者De Munck, S, Savvides, S.N.
登録日2021-03-17
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
7NX0
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LTK:ALKAL1 complex stabilized by a Nanobody
分子名称: ALK and LTK ligand 1, Leukocyte tyrosine kinase receptor, Nb3.16, ...
著者De Munck, S, Savvides, S.N.
登録日2021-03-17
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
7NX4
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Crystal structure of the TG and EGF-like domains of ALK
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor, NICKEL (II) ION, ...
著者De Munck, S, Savvides, S.N.
登録日2021-03-17
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
7NWZ
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BU of 7nwz by Molmil
ALK:ALKAL2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK and LTK ligand 2, ALK tyrosine kinase receptor
著者De Munck, S, Savvides, S.N.
登録日2021-03-17
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
7NX1
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TG domain of LTK
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Leukocyte tyrosine kinase receptor, TERBIUM(III) ION
著者De Munck, S, Savvides, S.N.
登録日2021-03-17
公開日2021-10-27
最終更新日2021-12-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
4CSO
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BU of 4cso by Molmil
The structure of OrfY from Thermoproteus tenax
分子名称: ORFY PROTEIN, TRANSCRIPTION FACTOR
著者Zeth, K, Hagemann, A, Siebers, B, Martin, J, Lupas, A.N.
登録日2014-03-09
公開日2014-03-19
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10.
Proteins, 82 Suppl 2, 2014
4DEP
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BU of 4dep by Molmil
Structure of the IL-1b signaling complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, Interleukin-1 receptor accessory protein, ...
著者Thomas, C, Garcia, K.C.
登録日2012-01-21
公開日2012-03-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the activating IL-1 receptor signaling complex.
Nat.Struct.Mol.Biol., 19, 2012
2HDE
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BU of 2hde by Molmil
Solution Structure of Human SAP18
分子名称: Histone deacetylase complex subunit SAP18
著者McCallum, S.A, Yin, J.P, Pan, B, Fairbrother, W.J.
登録日2006-06-20
公開日2007-04-24
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Structure of SAP18: a ubiquitin fold in histone deacetylase complex assembly.
Biochemistry, 45, 2006
2KLL
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BU of 2kll by Molmil
Solution structure of human interleukin-33
分子名称: Interleukin-33
著者Lingel, A, Fairbrother, W.
登録日2009-07-06
公開日2009-11-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes.
Structure, 17, 2009
3HO4
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BU of 3ho4 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP)
分子名称: Hedgehog-interacting protein
著者Hymowitz, S.G, Bosanac, I.
登録日2009-06-01
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
3HO3
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Crystal structure of Hedgehog-interacting protein (HHIP)
分子名称: Hedgehog-interacting protein
著者Bosanac, I, Hymowitz, S.G.
登録日2009-06-01
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009

 

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