1.5A Crystal Structure of the Nogo Receptor Ligand Binding Domain Reveals a Convergent Recognition Scaffold Mediating Inhibition of Myelination

Summary for 1OZN

DescriptorReticulon 4 receptor, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ALPHA-D-MANNOSE, ... (7 entities in total)
Functional Keywordsnogo receptor, mad, myelination inhibition, omgp, mag, nogo-66, p75, signal transduction, neuronal regeneration, ligand binding, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor, GPI-anchor Q9BZR6
Total number of polymer chains1
Total molecular weight33218.83
He, X.,Bazan, J.F.,Park, J.B.,McDermott, G.,He, Z.,Garcia, K.C. (deposition date: 2003-04-09, release date: 2003-05-20, Last modification date: 2011-07-13)
Primary citation
He, X.L.,Bazan, J.F.,McDermott, G.,Park, J.B.,Wang, K.,Tessier-Lavigne, M.,He, Z.,Garcia, K.C.
Structure of the Nogo Receptor Ectodomain. A Recognition module implicated in Myelin Inhibition.
Neuron, 38:177-185, 2003
PubMed: 12718853 (PDB entries with the same primary citation)
DOI: 10.1016/S0896-6273(03)00232-0
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers901.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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