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1OZN

1.5A Crystal Structure of the Nogo Receptor Ligand Binding Domain Reveals a Convergent Recognition Scaffold Mediating Inhibition of Myelination

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Reticulon 4 receptorpolymer28531613.41UniProt (Q9BZR6)
Pfam (PF13855)
Homo sapiens (human)Nogo receptor, NgR, Nogo-66 receptor
2B
(B)
alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G46299JT)
3C
(C)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G35926TG)
4D, E, F
(A)
ACETIC ACIDnon-polymer60.13Chemie (ACY)
5G
(A)
waterwater18.0354Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31613.4
BranchedNumber of molecules2
Total formula weight1335.2
Non-Polymers*Number of molecules3
Total formula weight180.2
All*Total formula weight33128.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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