1OZN
1.5A Crystal Structure of the Nogo Receptor Ligand Binding Domain Reveals a Convergent Recognition Scaffold Mediating Inhibition of Myelination
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Reticulon 4 receptor | polymer | 285 | 31613.4 | 1 | UniProt (Q9BZR6) Pfam (PF13855) In PDB | Homo sapiens (human) | Nogo receptor, NgR, Nogo-66 receptor |
2 | B | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G46299JT) | |||
3 | C | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G35926TG) | |||
4 | A | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
5 | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31613.4 | |
Branched | Number of molecules | 2 |
Total formula weight | 1335.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 180.2 | |
All* | Total formula weight | 33128.8 |