7DAV
| The native crystal structure of COVID-19 main protease | Descriptor: | COVID-19 MAIN PROTEASE | Authors: | He, Z.S, He, B, Cao, P, Jiang, H.D, Gong, Y, Gao, X.Y. | Deposit date: | 2020-10-18 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster. Nano Today, 44, 2022
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7DAT
| The crystal structure of COVID-19 main protease treated by AF | Descriptor: | COVID-19 MAIN PROTEASE, GOLD ION | Authors: | He, Z.S, He, B, Cao, P, Jiang, H.D, Gong, Y, Gao, X.Y. | Deposit date: | 2020-10-18 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster. Nano Today, 44, 2022
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7DAU
| The crystal structure of COVID-19 main protease treated by GA | Descriptor: | COVID-19 MAIN PROTEASE, GOLD ION | Authors: | He, Z.S, He, B, Cao, P, Jiang, H.D, Gong, Y, Gao, X.Y. | Deposit date: | 2020-10-18 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster. Nano Today, 44, 2022
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7X1R
| Cryo-EM structure of human thioredoxin reductase bound by Au | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, Thioredoxin reductase 1, ... | Authors: | He, Z.S, Cao, P, Cao, S.H, He, B, Jiang, H.D, Gong, Y, Gao, X.Y. | Deposit date: | 2022-02-24 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Au4 cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189 Nano Today, 47, 2022
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5D1I
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7Y1P
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8F7C
| Cryo-EM structure of human pannexin 2 | Descriptor: | Pannexin-2, Soluble cytochrome b562 fusion | Authors: | He, Z, Yuan, P. | Deposit date: | 2022-11-18 | Release date: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural and functional analysis of human pannexin 2 channel. Nat Commun, 14, 2023
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8WG5
| Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. | Deposit date: | 2023-09-20 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome To Be Published
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1OZN
| 1.5A Crystal Structure of the Nogo Receptor Ligand Binding Domain Reveals a Convergent Recognition Scaffold Mediating Inhibition of Myelination | Descriptor: | ACETIC ACID, Reticulon 4 receptor, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | He, X, Bazan, J.F, Park, J.B, McDermott, G, He, Z, Garcia, K.C. | Deposit date: | 2003-04-09 | Release date: | 2003-05-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structure of the Nogo Receptor Ectodomain. A Recognition module implicated in Myelin Inhibition. Neuron, 38, 2003
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6UZY
| Cryo-EM structure of Xenopus tropicalis pannexin 1 | Descriptor: | HEXADECANE, Pannexin, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Deng, Z, He, Z, Yuan, P. | Deposit date: | 2019-11-15 | Release date: | 2020-04-01 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structures of the ATP release channel pannexin 1. Nat.Struct.Mol.Biol., 27, 2020
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6V6D
| Cryo-EM structure of human pannexin 1 | Descriptor: | Pannexin-1 | Authors: | Deng, Z, He, Z, Yuan, P. | Deposit date: | 2019-12-05 | Release date: | 2020-04-01 | Last modified: | 2020-04-22 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Cryo-EM structures of the ATP release channel pannexin 1. Nat.Struct.Mol.Biol., 27, 2020
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8IUF
| Cryo-EM structure of Euglena gracilis super-complex I+III2+IV, composite | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Wu, M.C, Tian, H.T, He, Z.X, Hu, Y.Q, Zhou, L. | Deposit date: | 2023-03-24 | Release date: | 2024-02-28 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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8Y4U
| Crystal structure of a His1 from oryza sativa | Descriptor: | FE (III) ION, Fe(II)/2-oxoglutarate-dependent oxygenase | Authors: | Wang, N, Ma, J.M, Shibing, H, Beibei, Y, He, Z, Dandan, L. | Deposit date: | 2024-01-30 | Release date: | 2024-02-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of HPPD inhibitor sensitive protein from Oryza sativa. Biochem.Biophys.Res.Commun., 704, 2024
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8J9I
| Cryo-EM structure of Euglena gracilis complex I, turnover state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2023-05-03 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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8J9H
| Cryo-EM structure of Euglena gracilis respiratory complex I, deactive state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2023-05-03 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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8J9J
| Cryo-EM structure of Euglena gracilis complex I, NADH state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2023-05-03 | Release date: | 2024-02-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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8IUJ
| Cryo-EM structure of Euglena gracilis super-complex III2+IV2, composite | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Wu, M.C, Tian, H.T, He, Z.X, Hu, Y.Q, Zhou, L. | Deposit date: | 2023-03-24 | Release date: | 2024-02-28 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism. Nat Commun, 15, 2024
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4JKZ
| Crystal structure of ms6564 from mycobacterium smegmatis | Descriptor: | Transcriptional regulator, TetR family | Authors: | Yang, S.F, Gao, Z.Q, He, Z.G, Dong, Y.H. | Deposit date: | 2013-03-12 | Release date: | 2013-06-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for interaction between Mycobacterium smegmatis Ms6564, a TetR family master regulator, and its target DNA. J.Biol.Chem., 288, 2013
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4JL3
| Crystal structure of ms6564-dna complex | Descriptor: | DNA (31-MER), Transcriptional regulator, TetR family | Authors: | Yang, S.F, Gao, Z.Q, He, Z.G, Dong, Y.H. | Deposit date: | 2013-03-12 | Release date: | 2013-06-26 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for interaction between Mycobacterium smegmatis Ms6564, a TetR family master regulator, and its target DNA. J.Biol.Chem., 288, 2013
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7EG6
| Snf5 Finger Helix bound to the nucleosome | Descriptor: | DNA (235-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. | Deposit date: | 2021-03-24 | Release date: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
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7EGP
| The structure of SWI/SNF-nucleosome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ... | Authors: | Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. | Deposit date: | 2021-03-24 | Release date: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
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7EGM
| The SRM module of SWI/SNF-nucleosome complex | Descriptor: | SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF chromatin-remodeling complex subunit SWI1, SWI/SNF complex subunit SWI3, ... | Authors: | Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. | Deposit date: | 2021-03-24 | Release date: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
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6BNB
| Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET57 PROTAC | Descriptor: | Bromodomain-containing protein 4, DNA damage-binding protein 1, Protein cereblon, ... | Authors: | Nowak, R.P, DeAngelo, S.L, Buckley, D, Ishoey, M, He, Z, Zhang, T, Bradner, J.E, Fischer, E.S. | Deposit date: | 2017-11-16 | Release date: | 2018-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (6.343 Å) | Cite: | Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat. Chem. Biol., 14, 2018
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