8WG5
Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome
Summary for 8WG5
Entry DOI | 10.2210/pdb8wg5/pdb |
EMDB information | 37503 |
Descriptor | Ubiquitin carboxyl-terminal hydrolase 16, Histone H3.1, Histone H4, ... (8 entities in total) |
Functional Keywords | nucleosome complex, usp16, h2ak119ub, nuclear protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 279465.57 |
Authors | Ai, H.S.,He, Z.Z.,Deng, Z.H.,Liu, L. (deposition date: 2023-09-20, release date: 2023-12-27, Last modification date: 2024-07-10) |
Primary citation | Ai, H.,He, Z.,Deng, Z.,Chu, G.C.,Shi, Q.,Tong, Z.,Li, J.B.,Pan, M.,Liu, L. Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38918638DOI: 10.1038/s41594-024-01342-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.05 Å) |
Structure validation
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