8WG5
Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | M | Ubiquitin carboxyl-terminal hydrolase 16 | polymer | 823 | 93708.3 | 1 | UniProt (Q9Y5T5) Pfam (PF02148) Pfam (PF00443) In PDB | Homo sapiens (human) | Deubiquitinating enzyme 16,Ubiquitin thioesterase 16,Ubiquitin-processing protease UBP-M,Ubiquitin-specific-processing protease 16 |
| 2 | A, E | Histone H3.1 | polymer | 98 | 11562.6 | 2 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 3 | B, F | Histone H4 | polymer | 79 | 9010.5 | 2 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (human) | |
| 4 | C, G | Histone H2A type 1-B/E | polymer | 111 | 12141.2 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 5 | D, H | Histone H2B type 1-K | polymer | 94 | 10478.0 | 2 | UniProt (O60814) Pfam (PF00125) In PDB | Homo sapiens (human) | H2B K,HIRA-interacting protein 1 |
| 6 | I | DNA (147-MER) | polymer | 147 | 45604.0 | 1 | Homo sapiens (human) | ||
| 7 | J | DNA (147-MER) | polymer | 147 | 45145.8 | 1 | Homo sapiens (human) | ||
| 8 | U | Ubiquitin B | polymer | 76 | 8622.9 | 1 | UniProt (J3QS39) Pfam (PF00240) UniProt (by SIFTS) (P0CG47) In PDB | Homo sapiens (human) |
Sequence modifications
C, G: 10 - 118 (UniProt: P04908)
U: 1 - 75 (UniProt: J3QS39)
| PDB | External Database | Details |
|---|---|---|
| Cys 119 | - | expression tag |
| Thr 120 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Cys 76 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 279465.6 | |
| All* | Total formula weight | 279465.6 |
