7NX0

LTK:ALKAL1 complex stabilized by a Nanobody

Summary for 7NX0

• Entry DOI: 10.2210/pdb7nx0/pdb
• Related: 7NWZ 7NX1 7NX2 7NX3 7NX4
• Descriptor: Leukocyte tyrosine kinase receptor, Nb3.16, ALK and LTK ligand 1, ... (5 entities in total)
• Functional Keywords: cell surface receptor cytokine binding cytokine receptor complex, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 100657.02

Authors

De Munck, S.,Savvides, S.N. (deposition date: 2021-03-17, release date: 2021-10-27, Last modification date: 2024-01-31)

• Primary citation: De Munck, S.,Provost, M.,Kurikawa, M.,Omori, I.,Mukohyama, J.,Felix, J.,Bloch, Y.,Abdel-Wahab, O.,Bazan, J.F.,Yoshimi, A.,Savvides, S.N.; Structural basis of cytokine-mediated activation of ALK family receptors.; Nature, 600:143-147, 2021; PubMed: 34646012; DOI: 10.1038/s41586-021-03959-5

Experimental method

X-RAY DIFFRACTION (1.95 Å)