7NX0

LTK:ALKAL1 complex stabilized by a Nanobody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (C, B)	Leukocyte tyrosine kinase receptor	polymer	322	32069.8	2	UniProt (P29376) Pfam (PF12810)	Homo sapiens (Human)	Protein tyrosine kinase 1
2	B, D (D, E)	Nb3.16	polymer	126	13690.1	2		Lama glama
3	E (A)	ALK and LTK ligand 1	polymer	79	9045.2	1	UniProt (Q6UXT8) Pfam (PF15129)	Homo sapiens (Human)	Augmentor beta,AUG-beta,Protein FAM150A
4	F, G, H, I (C, B)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
5	J, K, L, M, N (C, D, B, E, A)	water	water		18.0	678	Chemie (HOH)

Sequence modifications

C, B: 63 - 378 (UniProt: P29376)

PDB	External Database	Details
Gly 379	-	expression tag
Thr 380	-	expression tag
Asp 381	-	expression tag
Glu 382	-	expression tag
Val 383	-	expression tag
Asp 384	-	expression tag

A: 57 - 129 (UniProt: Q6UXT8)

PDB	External Database	Details
Gly 130	-	expression tag
Thr 131	-	expression tag
Asp 132	-	expression tag
Glu 133	-	expression tag
Val 134	-	expression tag
Asp 135	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	100565.1
Non-Polymers*	Number of molecules	4
	Total formula weight	92.0
All*	Total formula weight	100657.0

*Water molecules are not included.