7NX0
LTK:ALKAL1 complex stabilized by a Nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C, B | Leukocyte tyrosine kinase receptor | polymer | 322 | 32069.8 | 2 | UniProt (P29376) Pfam (PF12810) In PDB | Homo sapiens (Human) | Protein tyrosine kinase 1 |
| 2 | D, E | Nb3.16 | polymer | 126 | 13690.1 | 2 | Lama glama | ||
| 3 | A | ALK and LTK ligand 1 | polymer | 79 | 9045.2 | 1 | UniProt (Q6UXT8) Pfam (PF15129) In PDB | Homo sapiens (Human) | Augmentor beta,AUG-beta,Protein FAM150A |
| 4 | C, B | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 678 | Chemie (HOH) |
Sequence modifications
C, B: 63 - 378 (UniProt: P29376)
A: 57 - 129 (UniProt: Q6UXT8)
| PDB | External Database | Details |
|---|---|---|
| Gly 379 | - | expression tag |
| Thr 380 | - | expression tag |
| Asp 381 | - | expression tag |
| Glu 382 | - | expression tag |
| Val 383 | - | expression tag |
| Asp 384 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 130 | - | expression tag |
| Thr 131 | - | expression tag |
| Asp 132 | - | expression tag |
| Glu 133 | - | expression tag |
| Val 134 | - | expression tag |
| Asp 135 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 100565.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 92.0 | |
| All* | Total formula weight | 100657.0 |
