3HO3
Crystal structure of Hedgehog-interacting protein (HHIP)
Summary for 3HO3
| Entry DOI | 10.2210/pdb3ho3/pdb |
| Related | 3HO4 3HO5 |
| Descriptor | Hedgehog-interacting protein (1 entity in total) |
| Functional Keywords | receptor ectodomain, six-bladed-propeller domain, egf domain, disulfide bond, cell membrane, egf-like domain, glycoprotein, membrane, secreted, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Peripheral membrane protein (By similarity). Isoform 2: Cytoplasm (Probable): Q96QV1 |
| Total number of polymer chains | 1 |
| Total formula weight | 54087.25 |
| Authors | Bosanac, I.,Hymowitz, S.G. (deposition date: 2009-06-01, release date: 2009-06-23, Last modification date: 2023-09-06) |
| Primary citation | Bosanac, I.,Maun, H.R.,Scales, S.J.,Wen, X.,Lingel, A.,Bazan, J.F.,de Sauvage, F.J.,Hymowitz, S.G.,Lazarus, R.A. The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling. Nat.Struct.Mol.Biol., 16:691-697, 2009 Cited by PubMed: 19561609DOI: 10.1038/nsmb.1632 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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