2KC9
 
 | |
6JKP
 | | Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense in complex with NAD+ | | Descriptor: | Methanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | | Authors: | Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z. | | Deposit date: | 2019-03-01 | | Release date: | 2019-06-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.008 Å) | | Cite: | Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense.
Biosci.Rep., 39, 2019
|
|
6JKO
 | | Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense | | Descriptor: | Methanol dehydrogenase, ZINC ION | | Authors: | Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z. | | Deposit date: | 2019-03-01 | | Release date: | 2019-06-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense.
Biosci.Rep., 39, 2019
|
|
3NR9
 | | Structure of human CDC2-like kinase 2 (CLK2) | | Descriptor: | (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Dual specificity protein kinase CLK2 | | Authors: | Chaikuad, A, Savitsky, P, Krojer, T, Muniz, J.R.C, Filippakopoulos, P, Rellos, P, Keates, T, Fedorov, O, Pike, A.C.W, Eswaran, J, Berridge, G, Phillips, C, Zhang, Y, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2010-06-30 | | Release date: | 2010-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structure of human CDC2-like kinase 2 (CLK2)
To be Published
|
|
3NPR
 | | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from S. aureus complexed with Presqualene diphosphate (PSPP) | | Descriptor: | Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | | Authors: | Lin, F.-Y, Liu, C.-I, Liu, Y.-L, Wang, K, Zhang, Y, Oldfield, E. | | Deposit date: | 2010-06-28 | | Release date: | 2010-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3NRI
 | | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from S. aureus complexed with dehydrosqualene (DHS) | | Descriptor: | (6E,10R,13S,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,11,13,14,18,22-octaene, Dehydrosqualene synthase | | Authors: | Lin, F.-Y, Liu, C.-I, Liu, Y.-L, Wang, K, Zhang, Y, Oldfield, E. | | Deposit date: | 2010-06-30 | | Release date: | 2010-12-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
6K3Z
 | | Crystal structure of dCas9 in complex with sgRNA and DNA (TGA PAM) | | Descriptor: | CRISPR-associated endonuclease Cas9, DNA (28-MER), DNA (5'-D(*AP*AP*AP*TP*GP*AP*TP*AP*TP*TP*G)-3'), ... | | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | Deposit date: | 2019-05-22 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
|
|
6K4P
 | | Crystal structure of xCas9 in complex with sgRNA and DNA (TGG PAM) | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), PHOSPHATE ION, ... | | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | Deposit date: | 2019-05-25 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
|
|
6K4U
 | | Crystal structure of xCas9 in complex with sgRNA and DNA (TGA PAM) | | Descriptor: | CRISPR-associated endonuclease Cas9, non-target DNA, sgRNA, ... | | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | Deposit date: | 2019-05-27 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
|
|
6K4S
 | | Crystal structure of xCas9 in complex with sgRNA and DNA (TGC PAM) | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, non-targeted DNA, sgRNA, ... | | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | Deposit date: | 2019-05-26 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
|
|
6K57
 | | Crystal structure of dCas9 in complex with sgRNA and DNA (CGA PAM) | | Descriptor: | CRISPR-associated endonuclease Cas9, non-target DNA, sgRNA, ... | | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | Deposit date: | 2019-05-28 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
|
|
3CIU
 | | Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic | | Descriptor: | 5-(2,5-dioxopyrrolidin-1-yl)-N-[2-(2-{2-[(4-O-alpha-D-idopyranosyl-alpha-D-mannopyranosyl)oxy]ethoxy}ethoxy)ethyl]pentanamide, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Bhatt, V.S, Zhang, Y, Sun, G, Wang, P.G, Palmer, A.F. | | Deposit date: | 2008-03-11 | | Release date: | 2008-04-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic
To be Published
|
|
6K4Q
 | | Crystal structure of xCas9 in complex with sgRNA and DNA (CGG PAM) | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*CP*GP*GP*TP*AP*TP*TP*G)-3'), ... | | Authors: | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | Deposit date: | 2019-05-26 | | Release date: | 2019-09-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
|
|
6K61
 | | Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120 | | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | Authors: | Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N. | | Deposit date: | 2019-05-31 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.37 Å) | | Cite: | Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria.
Nat.Plants, 5, 2019
|
|
3BGW
 | | The Structure Of A DnaB-Like Replicative Helicase And Its Interactions With Primase | | Descriptor: | DNAB-Like Replicative Helicase | | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | Deposit date: | 2007-11-27 | | Release date: | 2007-12-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.91 Å) | | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
|
|
6LON
 | | Crystal structure of HPSG | | Descriptor: | (2~{S})-2,3-bis(oxidanyl)propane-1-sulfonic acid, GLYCEROL, PFL2/glycerol dehydratase family glycyl radical enzyme, ... | | Authors: | Liu, J, Zhang, Y, Yuchi, Z. | | Deposit date: | 2020-01-06 | | Release date: | 2020-06-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3BH0
 | | ATPase Domain of G40P | | Descriptor: | DNAB-LIKE REPLICATIVE HELICASE | | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | Deposit date: | 2007-11-27 | | Release date: | 2007-12-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
|
|
4KYS
 | | Clostridium botulinum thiaminase I in complex with thiamin | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CITRIC ACID, MAGNESIUM ION, ... | | Authors: | Sikowitz, M.D, Shome, B, Zhang, Y, Begley, T.P, Ealick, S.E. | | Deposit date: | 2013-05-29 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structure of a Clostridium botulinum C143S Thiaminase I/Thiamin Complex Reveals Active Site Architecture.
Biochemistry, 52, 2013
|
|
3QH6
 | | 1.8A resolution structure of CT296 from Chlamydia trachomatis | | Descriptor: | CT296, TETRAETHYLENE GLYCOL | | Authors: | Kemege, K, Hickey, J, Lovell, S, Battaile, K.P, Zhang, Y, Hefty, P.S. | | Deposit date: | 2011-01-25 | | Release date: | 2011-10-05 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes.
J.Bacteriol., 193, 2011
|
|
8H02
 | |
8ISS
 | | Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution | | Descriptor: | MAGNESIUM ION, RNA (88-MER), tRNA-splicing endonuclease subunit Sen15, ... | | Authors: | Sun, Y, Zhang, Y, Yuan, L, Han, Y. | | Deposit date: | 2023-03-21 | | Release date: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex.
Nat Commun, 14, 2023
|
|
8IFG
 | | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | | Descriptor: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | | Authors: | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | | Deposit date: | 2023-02-17 | | Release date: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Class I histone deacetylase complex: Structure and functional correlates.
Proc Natl Acad Sci U S A, 120, 2023
|
|
8IKJ
 | | Cryo-EM structure of the inactive CD97 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor E5,Soluble cytochrome b562,Adhesion G protein-coupled receptor E5 subunit beta | | Authors: | Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P, Guo, J, Qin, J, Shen, D, Ji, S, Zang, S, Zhang, H, Wang, W, Shen, Q, Sun, P, Zhang, Y. | | Deposit date: | 2023-02-28 | | Release date: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Conformational transitions and activation of the adhesion receptor CD97.
Mol.Cell, 84, 2024
|
|
5H3D
 | | Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation | | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | | Authors: | Chan, C, Pang, X.Y, Zhang, Y, Sun, F, Fan, J. | | Deposit date: | 2016-10-22 | | Release date: | 2019-01-16 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (14 Å) | | Cite: | ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages.
Plos Comput.Biol., 15, 2019
|
|
3QH7
 | | 2.5 A resolution structure of Se-Met labeled CT296 from Chlamydia trachomatis | | Descriptor: | CT296 | | Authors: | Kemege, K, Hickey, J, Lovell, S, Battaile, K.P, Zhang, Y, Hefty, P.S. | | Deposit date: | 2011-01-25 | | Release date: | 2011-10-05 | | Last modified: | 2018-10-10 | | Method: | X-RAY DIFFRACTION (2.497 Å) | | Cite: | Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes.
J. Bacteriol., 193, 2011
|
|
