6K4P
Crystal structure of xCas9 in complex with sgRNA and DNA (TGG PAM)
Summary for 6K4P
Entry DOI | 10.2210/pdb6k4p/pdb |
Descriptor | sgRNA, DNA (28-MER), non-targeted DNA, ... (6 entities in total) |
Functional Keywords | endonuclease, hydrolase-dna-rna complex, hydrolase/dna/rna |
Biological source | Streptococcus pyogenes serotype M1 More |
Total number of polymer chains | 4 |
Total formula weight | 198421.89 |
Authors | |
Primary citation | Chen, W.,Zhang, H.,Zhang, Y.,Wang, Y.,Gan, J.,Ji, Q. Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17:e3000496-e3000496, 2019 Cited by PubMed: 31603896DOI: 10.1371/journal.pbio.3000496 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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