3NR9

Structure of human CDC2-like kinase 2 (CLK2)

Summary for 3NR9

• Entry DOI: 10.2210/pdb3nr9/pdb
• Descriptor: Dual specificity protein kinase CLK2, (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one (3 entities in total)
• Functional Keywords: structural genomics consortium, sgc, protein kinase, dual specificity protein kinase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Nucleus. Isoform 2: Nucleus speckle: P49760
• Total number of polymer chains: 3
• Total formula weight: 131218.88

Authors

Chaikuad, A.,Savitsky, P.,Krojer, T.,Muniz, J.R.C.,Filippakopoulos, P.,Rellos, P.,Keates, T.,Fedorov, O.,Pike, A.C.W.,Eswaran, J.,Berridge, G.,Phillips, C.,Zhang, Y.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-06-30, release date: 2010-08-25, Last modification date: 2023-09-06)

• Primary citation: Chaikuad, A.,Savitsky, P.,Krojer, T.,Muniz, J.R.C.,Filippakopoulos, P.,Rellos, P.,Keates, T.,Fedorov, O.,Pike, A.C.W.,Eswaran, J.,Berridge, G.,Phillips, C.,Zhang, Y.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Structure of human CDC2-like kinase 2 (CLK2); To be Published,

Experimental method

X-RAY DIFFRACTION (2.89 Å)