8IFG

Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe

Summary for 8IFG

• Entry DOI: 10.2210/pdb8ifg/pdb
• EMDB information: 35416 35417 36278
• Descriptor: RbAp48-related WD40 repeat-containing protein prw1, Paired amphipathic helix protein pst2, Histone deacetylase clr6, ... (8 entities in total)
• Functional Keywords: rpd3s, histone deacetylase, hdac, clr6, rpd3, clr6s, clr6 hdac, transcription
• Biological source: Schizosaccharomyces pombe (strain 972 / ATCC 24843); More
• Total number of polymer chains: 7
• Total formula weight: 411810.32

Authors

Zhang, H.Q.,Wang, X.,Wang, Y.N.,Liu, S.M.,Zhang, Y.,Xu, K.,Ji, L.T.,Kornberg, R.D. (deposition date: 2023-02-17, release date: 2024-01-03)

• Primary citation: Wang, X.,Wang, Y.,Liu, S.,Zhang, Y.,Xu, K.,Ji, L.,Kornberg, R.D.,Zhang, H.; Class I histone deacetylase complex: Structure and functional correlates.; Proc Natl Acad Sci U S A, 120:e2307598120-, 2023; PubMed: 37459529; DOI: 10.1073/pnas.2307598120

Experimental method

ELECTRON MICROSCOPY (3.2 Å)