5GRF
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5GRE
| Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), citrate and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ... | 著者 | Ma, T, Peng, Y, Ding, J. | 登録日 | 2016-08-11 | 公開日 | 2017-02-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 7, 2017
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5GRH
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5GRI
| Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and citrate | 分子名称: | CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | 著者 | Ma, T, Peng, Y, Ding, J. | 登録日 | 2016-08-11 | 公開日 | 2017-02-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 7, 2017
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5GRL
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5YVT
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5GZN
| Structure of neutralizing antibody bound to Zika envelope protein | 分子名称: | Antibody Heavy chain, Antibody light chain, Genome polyprotein | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2016-09-29 | 公開日 | 2016-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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5GZO
| Structure of neutralizing antibody bound to Zika envelope protein | 分子名称: | Antibody heavy chain, Antibody light chain, Genome polyprotein | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2016-09-29 | 公開日 | 2017-01-18 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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8GQU
| AK-42 inhibitor binding human ClC-2 TMD | 分子名称: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 | 著者 | Wang, L. | 登録日 | 2022-08-30 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42. Nat Commun, 14, 2023
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7XJA
| TMD masked refine map of human ClC-2 | 分子名称: | Chloride channel protein 2 | 著者 | Wang, L. | 登録日 | 2022-04-15 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14, 2023
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7XF5
| Full length human CLC-2 channel in apo state | 分子名称: | Chloride channel protein 2 | 著者 | Wang, L. | 登録日 | 2022-04-01 | 公開日 | 2023-05-03 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14, 2023
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6KDY
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6KE3
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6KDF
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6KDE
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6L57
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6L59
| Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with CIT, Mg and ATP binding at allosteric site and Mg, ATP binding at active site. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ... | 著者 | Sun, P, Ding, J. | 登録日 | 2019-10-22 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | 主引用文献 | Molecular mechanism of the dual regulatory roles of ATP on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 10, 2020
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8GRD
| Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | 著者 | Chen, X, Sun, P, Ding, J. | 登録日 | 2022-09-01 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GS5
| Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form | 分子名称: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... | 著者 | Sun, P, Chen, X, Ding, J. | 登録日 | 2022-09-04 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (4.486 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRG
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8GRH
| Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT | 分子名称: | CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... | 著者 | Sun, P, Chen, X, Ding, J. | 登録日 | 2022-09-01 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRU
| Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca | 分子名称: | CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... | 著者 | Sun, P, Chen, X, Ding, J. | 登録日 | 2022-09-02 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.847 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRB
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4NXL
| Dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | 分子名称: | DszC | 著者 | Zhang, L, Duan, X, Li, X, Rao, Z. | 登録日 | 2013-12-09 | 公開日 | 2014-07-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the stabilization of active, tetrameric DszC by its C-terminus. Proteins, 82, 2014
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5GZR
| Zika virus E protein complexed with a neutralizing antibody Z23-Fab | 分子名称: | Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ... | 著者 | Gao, G.G, Shi, Y, Peng, R, Liu, S. | 登録日 | 2016-10-01 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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