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6KE3

Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NADH

Summary for 6KE3
Entry DOI10.2210/pdb6ke3/pdb
DescriptorIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordsnad dependent isocitrate dehydrogenase, oxidoreductase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains8
Total formula weight308781.64
Authors
Sun, P.,Ding, J. (deposition date: 2019-07-03, release date: 2019-09-25, Last modification date: 2024-03-27)
Primary citationSun, P.,Ma, T.,Zhang, T.,Zhu, H.,Zhang, J.,Liu, Y.,Ding, J.
Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294:16214-16227, 2019
Cited by
PubMed: 31515270
DOI: 10.1074/jbc.RA119.010099
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.307 Å)
Structure validation

217705

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