4P48
| The structure of a chicken anti-cardiac Troponin I scFv | 分子名称: | Antibody scFv 180 | 著者 | Conroy, P.J, Law, R.H.P, Gillgunn, S, Hearty, S, Caradoc-Davies, T.T, Llyod, G, O'Kennedy, R.J, Whisstock, J.C. | 登録日 | 2014-03-12 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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4P49
| The structure of a chicken anti-prostate specific antigen scFv | 分子名称: | ACETATE ION, Antibody scFv B8, SULFATE ION | 著者 | Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C. | 登録日 | 2014-03-12 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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4Y1S
| Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes | 分子名称: | CALCIUM ION, Perforin-1 | 著者 | Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. | 登録日 | 2015-02-09 | 公開日 | 2015-09-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.611 Å) | 主引用文献 | Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015
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4Y1T
| Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes | 分子名称: | CALCIUM ION, Perforin-1 | 著者 | Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. | 登録日 | 2015-02-09 | 公開日 | 2015-09-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.666 Å) | 主引用文献 | Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015
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5FMW
| The poly-C9 component of the Complement Membrane Attack Complex | 分子名称: | POLYC9 | 著者 | Dudkina, N.V, Spicer, B.A, Reboul, C.F, Conroy, P.J, Lukoyanova, N, Elmlund, H, Law, R.H.P, Ekkel, S.M, Kondos, S.C, Goode, R.J.A, Ramm, G, Whisstock, J.C, Saibil, H.R, Dunstone, M.A. | 登録日 | 2015-11-10 | 公開日 | 2016-02-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structure of the Poly-C9 Component of the Complement Membrane Attack Complex Nat.Commun., 7, 2016
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5UG7
| Calcium bound Perforin C2 Domain - T431D | 分子名称: | CALCIUM ION, Perforin-1 | 著者 | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | 登録日 | 2017-01-07 | 公開日 | 2018-02-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
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5UG6
| Perforin C2 Domain - T431D | 分子名称: | IODIDE ION, Perforin-1 | 著者 | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | 登録日 | 2017-01-07 | 公開日 | 2018-02-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
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5VFX
| Structure of an accessory protein of the pCW3 relaxosome in complex with the origin of transfer (oriT) DNA | 分子名称: | TcpK, oriT | 著者 | Traore, D.A.K, Wisniewski, J.A, Flanigan, S.F, Conroy, P.J, Panjikar, S, Mok, Y.-F, Lao, C, Griffin, M.D.W, Adams, V, Rood, J.I, Whisstock, J.C. | 登録日 | 2017-04-10 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3. Nat Commun, 9, 2018
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5VFY
| Structure of an accessory protein of the pCW3 relaxosome | 分子名称: | TcpK | 著者 | Traore, D.A.K, Wisniewski, J.A, Flanigan, S.F, Conroy, P.J, Panjikar, S, Mok, Y.-F, Lao, C, Griffin, M.D.W, Adams, V, Rood, J.I, Whisstock, J.C. | 登録日 | 2017-04-10 | 公開日 | 2018-04-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3. Nat Commun, 9, 2018
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8DZV
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6OG4
| plasminogen binding group A streptococcal M protein | 分子名称: | Plasminogen, Plasminogen-binding group A streptococcal M-like protein PAM, SULFATE ION | 著者 | Law, R.H.P, Quek, A.J, Whisstock, J.C, Caradoc-Davies, T.T. | 登録日 | 2019-04-01 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding. J.Mol.Biol., 431, 2019
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5HN1
| Crystal structure of Interleukin-37 | 分子名称: | Interleukin-37, SULFATE ION | 著者 | Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C. | 登録日 | 2016-01-17 | 公開日 | 2017-02-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Homodimerization attenuates the anti-inflammatory activity of interleukin-37. Sci Immunol, 2, 2017
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6U2J
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6U2W
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6RSY
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6NMB
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6U23
| EM structure of MPEG-1(w.t.) soluble pre-pore | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein | 著者 | Pang, S.S, Bayly-Jones, C. | 登録日 | 2019-08-19 | 公開日 | 2019-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019
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6U2L
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6U2K
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5J7C
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6DLW
| Complement component polyC9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose | 著者 | Dunstone, M.A, Spicer, B.A, Law, R.H.P. | 登録日 | 2018-06-03 | 公開日 | 2018-09-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
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5J7K
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6CXO
| Complement component-9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ... | 著者 | Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T. | 登録日 | 2018-04-03 | 公開日 | 2018-09-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
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5UGG
| Protease Inhibitor | 分子名称: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(quinolin-2-yl)methyl]-L-tyrosinamide, Plasminogen | 著者 | Law, R.H.P, Wu, G, Whisstock, J.C. | 登録日 | 2017-01-08 | 公開日 | 2017-05-31 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
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5UGD
| Protease Inhibitor | 分子名称: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide, Plasminogen | 著者 | Law, R.H.P, Wu, G, Whisstock, J.C. | 登録日 | 2017-01-08 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
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