5HN1
Crystal structure of Interleukin-37
Summary for 5HN1
| Entry DOI | 10.2210/pdb5hn1/pdb |
| Descriptor | Interleukin-37, SULFATE ION (3 entities in total) |
| Functional Keywords | interleukin-1 cytokine inflammation interleukin-18, cytokine |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 39426.92 |
| Authors | Ellisdon, A.M.,Nold-Petry, C.A.,Nold, M.F.,Whisstock, J.C. (deposition date: 2016-01-17, release date: 2017-02-22, Last modification date: 2023-09-27) |
| Primary citation | Ellisdon, A.M.,Nold-Petry, C.A.,D'Andrea, L.,Cho, S.X.,Lao, J.C.,Rudloff, I.,Ngo, D.,Lo, C.Y.,Soares da Costa, T.P.,Perugini, M.A.,Conroy, P.J.,Whisstock, J.C.,Nold, M.F. Homodimerization attenuates the anti-inflammatory activity of interleukin-37. Sci Immunol, 2:-, 2017 Cited by PubMed: 28783685DOI: 10.1126/sciimmunol.aaj1548 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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