5HN1
Crystal structure of Interleukin-37
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005125 | molecular_function | cytokine activity |
| A | 0005149 | molecular_function | interleukin-1 receptor binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006954 | biological_process | inflammatory response |
| A | 0006955 | biological_process | immune response |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0005149 | molecular_function | interleukin-1 receptor binding |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006954 | biological_process | inflammatory response |
| B | 0006955 | biological_process | immune response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | LYS83 |
| A | ASN84 |
| B | ASP73 |
| B | SER74 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | ASP123 |
| A | LYS124 |
| A | HIS172 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG151 |
| A | GLU194 |
| A | HOH401 |
| A | HOH405 |
| A | HOH411 |
| A | HOH453 |
| A | LYS53 |
| A | GLU148 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | GLU138 |
| A | LYS139 |
| A | LYS142 |
| A | HOH423 |
| A | HOH462 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ARG158 |
